anti-STAT1 (STAT1) Antikörper

Bezeichnung:
anti-Signal Transducer and Activator of Transcription 1, 91kDa Antikörper (STAT1)
Auf www.antikoerper-online.de finden Sie aktuell 635 Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antikörper von 38 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen STAT1 Kits (46) und STAT1 Proteine (21) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 747 STAT1 Produkte verfügbar.
Synonyme:
2010005J02Rik, AA408197, CANDF7, DD6G4-4, dZ182H3.3, H2RSP, IMUP, IMUP-1, IMUP-2, ISGF-3, si:by51f19.1, si:by134g18.2, si:dz73o4.2, si:dz182h3.3, si:dz199m19.1, STAT, STAT1, STAT4, STAT91, XStat1
Alle Antikörper anzeigen Gen GeneID UniProt
STAT1 72275  
STAT1 25124  
STAT1 6772 P42224

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Am meisten referenzierte anti-STAT1 Antikörper

  1. Human Polyclonal STAT1 Primary Antibody für EIA, IHC (p) - ABIN358231 : Garcin, Marq, Iseni, Martin, Kolakofsky: A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability. in Journal of virology 2004 (PubMed)
    Zeige alle 5 Referenzen für 358231

  2. Human Polyclonal STAT1 Primary Antibody für IF (p), IHC (p) - ABIN674889 : Wang, Wang, Song, Chu, Qu: Deficiency of interferon-gamma or its receptor promotes colorectal cancer development. in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2015 (PubMed)
    Zeige alle 3 Referenzen für 674889

  3. Human Polyclonal STAT1 Primary Antibody für IF, IHC - ABIN1533008 : Durbin, Hackenmiller, Simon, Levy: Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. in Cell 1996 (PubMed)
    Zeige alle 2 Referenzen für 1533008

  4. Cow (Bovine) Polyclonal STAT1 Primary Antibody für IHC, WB - ABIN2780843 : Battle, Lynch, Frank: Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis. in Cancer research 2006 (PubMed)
    Zeige alle 2 Referenzen für 2780843

  5. Human Monoclonal STAT1 Primary Antibody für IHC (p), IP - ABIN269146 : Kovarik, Boudny, Kocak, Lauerova, Fait, Vagundova: Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. in International journal of molecular medicine 2003 (PubMed)
    Zeige alle 2 Referenzen für 269146

  6. Human Polyclonal STAT1 Primary Antibody für ELISA, WB - ABIN1533729 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

Weitere Antikörper gegen STAT1 Interaktionspartner

Mouse (Murine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. In cultured macrophages, LPS (zeige TLR4 Antikörper)-induced expression of monocyte chemoattractant protein (MCP)-1 (zeige CPT1B Antikörper) was suppressed by NaN3 through inhibition of STAT1 and IkappaBzeta (zeige NFKBIZ Antikörper) activities.

  2. Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting were used to detect the mRNA and protein expressions of p-p38MAPK (zeige MAPK14 Antikörper), AAT (zeige SERPINA1A Antikörper), signal transducer and activator of transcription 1 (STAT1) and activating transcription factor2 (ATF2 (zeige ATF2 Antikörper))

  3. This secreted effector, toxoplasma inhibitor of STAT1-dependent transcription (TgIST), translocates to the host cell nucleus, where it recruits mouse Mi-2 (zeige CHD4 Antikörper)/NuRD to STAT1-dependent promoters, resulting in altered chromatin and blocked transcription.

  4. Microbiome depletion as a result of broad-spectrum antibiotic treatment disrupts basal Stat1 signaling and alters T-cell homeostasis, leading to impaired progenitor maintenance and granulocyte maturation.

  5. We revealed that in mouse mesenchymal stem cells IFN-gamma-induced (zeige SAMHD1 Antikörper) immunoregulation is mediated by early phosphorylation of signal transducer and activator of transcription (STAT) 1 and STAT3 (zeige STAT3 Antikörper), which is significantly enhanced by an extracellular signal-regulated kinase 1/2 (zeige MAPK3 Antikörper)-dependent mTOR (zeige FRAP1 Antikörper) inhibition, thereby promoting pSTAT1 nuclear translocation.

  6. these results define a differential regulation of TLR-mediated activation and differentiation of MZ B cells by STAT1 and reveal a STAT1-dependent, but IFN-independent, antibody response during infection and inflammation.

  7. B cell-intrinsic IFN-gamma (zeige IFNG Antikörper) receptor (IFN-gammaR (zeige IFNGR1 Antikörper)) and STAT1 signaling are required for Spontaneously developed germinal centers and follicular T helper cell (Tfh cell) development.

  8. Inhibitor-sensitive tyrosine kinase (zeige TYRO3 Antikörper) controls the population heterogeneity of basal STAT1 activity in Ube1l (zeige UBA7 Antikörper) deficient fibroblasts.

  9. The studies presented here reveal that the ability of IFN-gamma (zeige IFNG Antikörper) to inhibit parasite replication in astrocytes in vitro is dependent on signal transducer and activator of transcription 1 (STAT1) and that mice that specifically lack STAT1 in astrocytes are unable to limit parasite replication in the central nervous system (CNS).

  10. We found that STAT-1(-/-) MRL lpr (zeige FAS Antikörper) mice, but not IRF-9 (zeige IRF9 Antikörper)(-/-) or IFNAR-2 (zeige IFNAR2 Antikörper)(-/-) mice, developed interstitial nephritis characterized by infiltration with RORgammat-positive lymphocytes, macrophages, and eosinophils. Despite pronounced interstitial kidney disease and abnormal kidney function, STAT-1(-/-) mice had decreased proteinuria, glomerulonephritis, and autoantibody production.

Human Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. MFSD2B, CCL20 (zeige CCL20 Antikörper) and STAT1, or STARD7 (zeige STARD7 Antikörper) and ZNF512 (zeige ZNF512 Antikörper) genes may be risk or protect factors in prognosis of ADC (zeige ADC Antikörper); HTR2B (zeige HTR2B Antikörper), DPP4 (zeige DPP4 Antikörper), and TGFBRAP1 (zeige TGFBRAP1 Antikörper) genes may be risk factors in prognosis of SQC (zeige QPCT Antikörper).

  2. In cultured macrophages, LPS (zeige IRF6 Antikörper)-induced expression of monocyte chemoattractant protein (MCP)-1 (zeige CCL2 Antikörper) was suppressed by NaN3 through inhibition of STAT1 and IkappaBzeta (zeige NFKBIZ Antikörper) activities.

  3. Functional analysis of NK cells shows a significant impairment of cytolytic and degranulation activities in chronic mucocutaneous candidiasis patients with STAT1 GOF mutations

  4. Mechanistic investigations reveal that AJUBA (zeige AJUBA Antikörper) specifically binds the FERM domain of JAK1 (zeige JAK1 Antikörper) to dissociate JAK1 (zeige JAK1 Antikörper) from the IFNgamma recepter, resulting in an inhibition of STAT1 phosporylation and concomitantly its nuclear translocation. Clinically, the level of AJUBA (zeige AJUBA Antikörper) in CRC (zeige CALR Antikörper) specimens is negatively correlated with the levels of IFIT2 (zeige IFIT2 Antikörper) and pSTAT1

  5. Low STAT1 expression is associated with Pancreatic cancer.

  6. STAT1 and IRF1 (zeige IRF1 Antikörper) collaborate to induce interferon-gamma (zeige IFNG Antikörper) stimulated genes (ISGs), but the extent to which they act alone or together is unclear.This study provides strong evidence for widespread cooperation between STAT1 and IRF1 (zeige IRF1 Antikörper) at ISGs, and suggests that in silico predictions reliably predict the effect of nucleotide variants on binding in vivo.

  7. IFITM1 (zeige IFITM1 Antikörper) suppression blocks proliferation and invasion of aromatase (zeige CYP19A1 Antikörper) inhibitor-resistant breast cancer in vivo by JAK (zeige JAK3 Antikörper)/STAT1-mediated induction of p21 (zeige CDKN1A Antikörper).

  8. This study reports a new role for SETD2 (zeige SETD2 Antikörper) in promoting IFNalpha-induced antiviral immune response by directly methylating STAT1 on lysine 525 and catalyzing H3K36me3 on the promoters of some IFN-stimulated genes (ISGs such as ISG15 (zeige ISG15 Antikörper)) to activate gene transcription. Thus, SETD2 (zeige SETD2 Antikörper) enhances host antiviral immunity by strengthening IFNalpha signaling both post-translationally and epigenetically.

  9. STAT1 gain-of-function mutations underlie Autosomal dominant chronic mucocutaneous candidiasis, as well as an unexpectedly wide range of other clinical features, including not only a variety of infectious and autoimmune diseases, but also cerebral aneurysms and carcinomas that confer a poor prognosis.

  10. Six different heterozygous mutations in STAT1 were detected in the seven patients (Patients 3 and 4 shared identical mutations). Three of these mutations were recurrent variants (p.R274Q, p.K388E and p.P329L), whereas the other three (p.N357D, p.M202T, and p.T437I), involving both the coiled coil domain (CCD (zeige RUNX2 Antikörper)) and DNA binding domain (DBD), have not been reported previously.

Pig (Porcine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (zeige IFNA Antikörper) response by inducing STAT1 degradation.

  2. this study shows that weaning caused severe inflammation associated with the suppression of STAT1 in the jejunum of piglets

  3. Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK (zeige JAK3 Antikörper)-STAT1) signaling pathway.

  4. Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 (zeige STAT2 Antikörper) nuclear translocation.

  5. Nsp1beta inhibits interferon-activated (zeige MNDA Antikörper) STAT1/STAT2 (zeige STAT2 Antikörper) signal transduction by inducing karyopherin-alpha1 degradation.

  6. STAT1 is involved in mediating the action of ghrelin (zeige GHRL Antikörper) on ovarian cell functions.

  7. the majority of the STAT1/STAT2 (zeige STAT2 Antikörper)/IRF9 (zeige IRF9 Antikörper) (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked

  8. Cell-type-specific expression of STAT1 highlight the complex interplay between endometrium and conceptus for pregnancy recognition and implantation.

  9. Nitric oxide-dependent increase in caspase-8 (zeige CASP8 Antikörper) mRNA levels is associated with phosphorylation of STAT-1 at Ser (zeige SIGLEC1 Antikörper)-727 and STAT1 binding to the caspase-8 (zeige CASP8 Antikörper) promoter in cultured lung endothelial cells.

  10. Activated STAT1 may be associated with or perhaps contribute to the structural and inflammatory changes in pacing-induced sustained atrial fibrillation.

Cow (Bovine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. Report interferon-tau dependent STAT1 regulation of SOCS (zeige CISH Antikörper) genes in bovine endometrium during estrus cycle and embryo implantation.

  2. the interaction between STAT1 SNP and SNP19069 was highly significant for survival rate

  3. results show for the first time that interleukin-6 (zeige IL6 Antikörper) (IL), in the presence of its soluble receptor (zeige IFNAR1 Antikörper) (sIL (zeige STIL Antikörper)-6R), induces activation of JAK1 (zeige JAK1 Antikörper), JAK2 (zeige JAK2 Antikörper), and STAT1/STAT3 (zeige STAT3 Antikörper) proteins in bovine articular chondrocytes

  4. Results from this study are consistent with previous studies on the role of STAT1 in regulating the transcription of genes involved in milk protein (zeige CSN2 Antikörper) synthesis and fat metabolism.

  5. Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2 (zeige STAT2 Antikörper).

STAT1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT1

  • signal transducer and activator of transcription 1, 91kDa (STAT1) Antikörper
  • RIKEN cDNA 2200002D01 gene (2200002D01Rik) Antikörper
  • signal transducer and activator of transcription 1 (Stat1) Antikörper
  • signal transducer and activator of transcription 1, 91kDa (stat1) Antikörper
  • signal transducer and activator of transcription 4 (stat4) Antikörper
  • 2010005J02Rik Antikörper
  • AA408197 Antikörper
  • CANDF7 Antikörper
  • DD6G4-4 Antikörper
  • dZ182H3.3 Antikörper
  • H2RSP Antikörper
  • IMUP Antikörper
  • IMUP-1 Antikörper
  • IMUP-2 Antikörper
  • ISGF-3 Antikörper
  • si:by51f19.1 Antikörper
  • si:by134g18.2 Antikörper
  • si:dz73o4.2 Antikörper
  • si:dz182h3.3 Antikörper
  • si:dz199m19.1 Antikörper
  • STAT Antikörper
  • STAT1 Antikörper
  • STAT4 Antikörper
  • STAT91 Antikörper
  • XStat1 Antikörper

Bezeichner auf Proteinebene für STAT1

signal transducer and activator of transcription 1-alpha/beta , HAI-2 related small protein , signal transducer and activator of transcription-1 , transcription factor ISGF-3 components p91/p84 , signal transducer and activator of transcription 4 , signal transducer and activator of transcription 1 , transcription factor ISGF-3 , activator of transcription , signal transduction

GENE ID SPEZIES
100307049 Ovis aries
72275 Mus musculus
20846 Mus musculus
25124 Rattus norvegicus
6772 Homo sapiens
424044 Gallus gallus
488449 Canis lupus familiaris
396655 Sus scrofa
510814 Bos taurus
398324 Xenopus laevis
100343893 Oryctolagus cuniculus
368519 Danio rerio
Ausgewählte Anbieter für anti-STAT1 (STAT1) Antikörper
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