Transcriptional Adaptor 3 Proteine (TADA3)

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

• transcriptional adaptor 3 (TADA3)
• transcriptional adaptor 3 (Tada3)
• transcriptional adaptor 3 (LOC732883)
• transcriptional adapter 3 pseudogene (LOC100061462)
• transcriptional adaptor 3 (tada3)
• Alle Gen-Bezeichnungen
• transcriptional adapter 3 pseudogene (LOC100619707)
• transcriptional adaptor 3 (NGG1 homolog, yeast)-like (tada3l)
• transcriptional adaptor 3 S homeolog (tada3.S)

• 1110004B19Rik Protein
• ada3 Protein
• ada3-B Protein
• AI987856 Protein
• fa03f04 Protein
• Alle Synonyme
• hADA3 Protein
• ngg1 Protein
• STAF54 Protein
• tada3 Protein
• tada3l Protein
• tada3l-B Protein
• wu:fa03f04 Protein
• zgc:63596 Protein

ADA3 homolog , ADA3-like protein , transcriptional adapter 3 , transcriptional adaptor 3 , transcriptional adapter 3-like , mADA3 , ADA3 homolog B , ADA3-like protein B , Transcriptional adapter 3-like B , transcriptional adapter 3-B