Kurzübersicht für Sodium valproate (ABIN7233292)
Applikation
Chemical Name
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Verwendungszweck
- HDAC inhibitor
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Produktmerkmale
- Histone deacetylase inhibitor (IC50 = 400μM). Demonstrates neuroprotective, anticancer, and anti-inflammatory activity. Inhibits Aβ production, reduced neuritic plaque formation, and improved memory deficits in Alzheimer's mouse models. Improves stem cell reprogramming efficiency and enables efficient induction of pluripotency without introduction of the oncogene c-Myc. Clinically useful anticonvulsant
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Reinheit
- >98 %
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Formel
- C8H15O2 Na
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Löslichkeit
- Soluble in Water (up to 50 mg/ml).
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
Anacardic AcidInh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
SAHA (Vorinostat)Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid
Phenylbutyrate NaInh 1716-12-7 4-Phenylbutyric acid, sodium salt
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Powder
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Lagerung
- -20 °C
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Hintergrund
- Valproic acid,Epigenetics,Autophagy,Protein deacetylase,Cell death,Stem cells,Neuroscience,Neurodegeneration,Posttranslational modification,Chromatin
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Molekulargewicht
- 166.20
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CAS-Nummer
- 1069-66-5
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