Ruxolitinib
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- Applikation
- Inhibition (Inh)
- Verwendungszweck
- JAK kinase inhibitor
- Reinheit
- >98 %
- Chemical Name
- (3R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
- Formel
- C17H18N6
- Löslichkeit
- Soluble in DMSO (25 mg/ml) or EtOH (~15 mg/ml)
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
Mithramycin AInh 18378-89-7
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- Kommentare
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Source: Synthetic.
Appearance: Off-white solid - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Solid
- Vorsichtsmaßnahmen
- Classification: Skin Corrosion/Irritation, Category 2 Serious Eye Damage/Eye Irritation, Category 1 Danger Target Organ Systemic Toxicity (repeated exposure), Category 2 Toxic To Reproduction, Category 2 Warning Acute Toxicity: Oral, Category 4 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H315: Causes skin irritation. H318: Causes serious eye damage H373: May cause damage to organs through prolonged or repeated exposure. H361: Suspected of damaging fertility or the unborn child. H302: Harmful if swallowed. Precautionary statements: P264: Wash hands thoroughly after handling. P280: Wear protective gloves/clothing and eye/face protection as specified by the manufacturer/supplier or the competent authority. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P302+352: IF ON SKIN: Wash with plenty of soap and water. P332+313: If skin irritation occurs, get medical advice/attention. P362: Take off contaminated clothing and wash before re-use. P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310: Immediately call a POISON CENTER or doctor/physician. P314: Get medical attentiodvice if you feel unwell. P308+313: IF exposed or concerned: Get medical attentiodvice. P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P330: Rinse mouth.
- Handhabung
- Classification: Skin Corrosion/Irritation, Category 2 Serious Eye Damage/Eye Irritation, Category 1 Danger Target Organ Systemic Toxicity (repeated exposure), Category 2 Toxic To Reproduction, Category 2 Warning Acute Toxicity: Oral, Category 4 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H315: Causes skin irritation. H318: Causes serious eye damage H373: May cause damage to organs through prolonged or repeated exposure. H361: Suspected of damaging fertility or the unborn child. H302: Harmful if swallowed. Precautionary statements: P264: Wash hands thoroughly after handling. P280: Wear protective gloves/clothing and eye/face protection as specified by the manufacturer/supplier or the competent authority. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P302+352: IF ON SKIN: Wash with plenty of soap and water. P332+313: If skin irritation occurs, get medical advice/attention. P362: Take off contaminated clothing and wash before re-use. P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310: Immediately call a POISON CENTER or doctor/physician. P314: Get medical attentiodvice if you feel unwell. P308+313: IF exposed or concerned: Get medical attentiodvice. P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P330: Rinse mouth.
- Lagerung
- -20 °C
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- Molekulargewicht
- 306.4
- CAS-Nummer
- 941678-49-5
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