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Flavopiridol (Alvocidib) HCl

InhA, Func 131740-09-5
Produktnummer ABIN4878150
  • Applikation
    Inhibition Assay (InhA), Functional Studies (Func)
    Verwendungszweck
    Alvocidib Hydrochloride is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity.
    Produktmerkmale
    Target: CDK inhibitor
    Receptor: CDK1,2,4,6
    Aufreinigung
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Reinheit
    99.31 %
    Formel
    C21H21Cl2NO5
    Löslichkeit
    Soluble in DMSO
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Solid
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Haltbarkeit
    24 months
  • Hintergrund
    Cell Cycle/Checkpoint
    Molekulargewicht
    438.30 g/mol
    CAS-Nummer
    131740-09-5
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