IL1RN Proteine
(Interleukin 1 Receptor Antagonist (IL1RN))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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IL1RN
Spezies: Kaninchen
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
IL1RN
Spezies: Schwein
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL1RN
Spezies: Hund
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL1RN
Spezies: Rind (Kuh)
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL1RN
Spezies: Pferd
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL1RN
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95% by SDS-PAGE
SDS, AcA
Active
IL1RN
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95% by SDS - PAGE
SDS, AcA
Active
IL1RN
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
Func, STD, AbP, PI
Active
1 image
IL1RN
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
IL1RN
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
IL1RN
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
IL1RN
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
IL1RN
Spezies: Hund
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
IL1RN
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % , as determined by Coomassie stained SDS-PAGE.
ELISA, FACS
Active
IL1RN
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>98 % , as determined by Coomassie stained SDS-PAGE and HPLC analysis.
FACS
Active
IL1RN
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
>97 % as determined by SDS-PAGE and HPLC.
Func
Active
IL1RN
Spezies: Maus
Wirt: Escherichia coli (E. coli)
> 95 %
AcA, CC
Active
IL1RN
Spezies: Human
Wirt: Escherichia coli (E. coli)
> 95 %
AcA, CC
Active
IL1RN
Spezies: Pferd
Wirt: Escherichia coli (E. coli)
Recombinant
>95 % as determined by SDS-PAGE and HPLC.
Func
Active
Aktuelle Publikationen für unsere IL1RN Proteine
: "Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages." in: Journal of virology, Vol. 94, Issue 17, (2020) (PubMed).: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).
: "The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling." in: Genes & development, Vol. 29, Issue 23, pp. 2475-89, (2015) (PubMed).
: "Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines." in: Gastroenterology, Vol. 143, Issue 6, pp. 1530-43, (2012) (PubMed).
: "Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26440-9, (2011) (PubMed).
: "Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis." in: Human molecular genetics, Vol. 19, Issue 13, pp. 2594-605, (2010) (PubMed).
: "Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 12, pp. 5232-6, (1991) (PubMed).
: "Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein." in: Nature, Vol. 344, Issue 6267, pp. 633-8, (1990) (PubMed).
Aliase für IL1RN Proteine
interleukin 1 receptor antagonist (IL1RN) Proteineinterleukin 1 receptor antagonist (Il1rn) Proteine
interleukin 1 receptor antagonist-like (IL1RNL) Proteine
DIRA Proteine
F630041P17Rik Proteine
ICIL-1RA Proteine
IL-1ra Proteine
IL-1RA Proteine
IL-1ra3 Proteine
IL-1RN Proteine
IL1F3 Proteine
IL1RA Proteine
IL1RN Proteine
IRAP Proteine
IRAP1 Proteine
MVCD4 Proteine
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- IL21 Receptor Proteine
- IL22 Receptor alpha 1 Proteine
- IL22RA2 Proteine
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- IL23A Proteine
- IL23R Proteine
- IL27 Receptor alpha Proteine
- IL28A Proteine
- IL28B Proteine
- IL28RA Proteine
- IL29 Proteine
- IL2RG Proteine
- IL31RA Proteine
- IL32 Proteine
- IL36A/IL1F6 Proteine
- IL3RA Proteine
- IL4 Receptor Proteine
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