IL-7 Proteine
(Interleukin 7 (IL7))
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010].
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48 Treffer
IL7
Spezies: Human
Wirt: CHO Cells
Recombinant
>98 % (SDS-PAGE)
Active
IL7
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL7
Spezies: Kaninchen
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
IL7
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
IL7
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
IL7
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
IL7
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS-PAGE
SDS
IL7
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
IL7
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS-PAGE
SDS, AcA
Active
IL7
Spezies: Human
Wirt: Escherichia coli (E. coli)
> 95 % by SDS-PAGE and HPLC analyses.
Active
Rockland 009-001-b94
IL7
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
98,00%
SDS
1 image
Rockland Original
IL7
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
Func, STD, AbP, PI
Active
1 image
IL7
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
1 image
IL7
Spezies: Maus
Wirt: Insektenzellen
Recombinant
> 95 % , as determined by Coomassie stained SDS-PAGE.
FACS
Active
IL7
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
< 98 % by SDS-PAGE gel and HPLC analyses.
Active
IL7
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>98 % , as determined by Coomassie stained SDS-PAGE and HPLC analysis.
WB, FACS, IP
Active
Rockland 010-001-b94-0020
IL7
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
98,00%
SDS
Rockland Original
IL7
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
IL7
Spezies: Maus
Wirt: Insektenzellen
Recombinant
> 95 % , as determined by Coomassie stained SDS-PAGE.
Func, STD, AbP, PI
Active
Aktuelle Publikationen für unsere IL-7 Proteine
: "gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis." in: Blood, Vol. 115, Issue 12, pp. 2380-90, (2010) (PubMed).: "Ikaros regulates Notch target gene expression in developing thymocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 9, pp. 6265-74, (2008) (PubMed).
: "Interleukin-7: a new hematopoietic growth factor." in: Progress in clinical and biological research, Vol. 338, pp. 65-73, (1990) (PubMed).
: "Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 302-6, (1989) (PubMed).
: "Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 16, pp. 5894-8, (1986) (PubMed).
Aliase für IL-7 Proteine
interleukin 7 (IL7) Proteineinterleukin 7 (Il7) Proteine
A630026I06Rik Proteine
hlb368 Proteine
IL-7 Proteine
Il-7 Proteine
IL7 Proteine
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