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IKZF1 Proteine

(IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
This gene encodes a transcription factor that belongs to the family of zinc-finger DNA binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. All isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homodimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and contain the nuclear localization signal, resulting in members with and without DNA-binding properties. Only few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and thought to function as dominant negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2011].

8 Treffer

custom-made IKZF1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7563588
 
custom-made IKZF1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7554142
 
IKZF1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Produktnummer ABIN7123400
 
IKZF1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Produktnummer ABIN1307650
 
IKZF1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant ELISA, WB, SDS
Produktnummer ABIN7577598
 
custom-made IKZF1 Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
Produktnummer ABIN3134815
 
custom-made IKZF1 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
Produktnummer ABIN3093023
 
IKZF1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2723364
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Escherichia coli (E. coli)
    • Wheat germ
  • Bindungsspezifität
    • AA 1-519
    • AA 1-517
    • AA 1-477
  • Konjugat
    • His tag
    • Strep Tag
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Hersteller
    • antibodies-online
    • OriGene

Aliase für IKZF1 Proteine

IKAROS family zinc finger 1 (IKZF1) Proteine
IKAROS family zinc finger 1 (Ikzf1) Proteine
IKAROS family zinc finger 1 (Ikaros) (ikzf1) Proteine
IKAROS family zinc finger 1 (ikzf1) Proteine
5832432G11Rik Proteine
hIk-1 Proteine
hik-1 Proteine
hlk-1 Proteine
Hs.54452 Proteine
hs.54452 Proteine
IK1 Proteine
ik1 Proteine
IKAROS Proteine
ikaros Proteine
Ikaros Proteine
ikzf1 Proteine
LyF-1 Proteine
LYF1 Proteine
lyf1 Proteine
MGC108252 Proteine
mKIAA4227 Proteine
PRO0758 Proteine
pro0758 Proteine
RGD1562979 Proteine
Zfpn1a1 Proteine
ZNFN1A1 Proteine
znfn1a1 Proteine
Znfn1a1 Proteine
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