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IDO Produkte

(Indoleamine 2,3-Dioxygenase (IDO))
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].

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Ausgewählte IDO Kategorien

IDO Antikörper

High quality antibodies with extensive validation data.

IDO ELISA Kits

Reliable ELISA kits for a wide range of species.

IDO Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene IDO Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Applikation ICC, IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN5013734
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Rat
Applikation ICC, IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN1174762
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
Kat. Nr. ABIN3029730
Menge 100 μg
Datenblatt Datenblatt

Empfohlene IDO ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (10)
  • (6)
Kat. Nr. ABIN6574282
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN6730945
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6956720
Menge 96 tests
Datenblatt Datenblatt

Empfohlene IDO Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (2)
Kat. Nr. ABIN6239816
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3009927
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3009928
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren IDO Produkten

Albejante, Kunz, Ferreira, Júnior, de Almeida, Bacigalupo, Matheus, Dalboni, Camacho, Dellê: "Proteinuria is Associated with Urinary Loss of Cubilin and Vitamin D-Binding Protein in Patients with Preeclampsia." in: Scientific reports, Vol. 10, Issue 1, pp. 3956, (2020) (PubMed).

Guastella, Michelhaugh, Klinger, Fadel, Kiousis, Ali-Fehmi, Kupsky, Juhász, Mittal: "Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors." in: Journal of neuro-oncology, Vol. 139, Issue 2, pp. 239-249, (2019) (PubMed).

Duda, Curzytek, Kubera, Connor, Fagan, Basta-Kaim, Trojan, Papp, Gruca, Budziszewska, Leśkiewicz, Maes, Lasoń: "Interaction of the immune-inflammatory and the kynurenine pathways in rats resistant to antidepressant treatment in model of depression." in: International immunopharmacology, Vol. 73, pp. 527-538, (2019) (PubMed).

Guastella, Michelhaugh, Klinger, Kupsky, Polin, Muzik, Juhász, Mittal: "Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma." in: Molecular imaging, Vol. 15, (2016) (PubMed).

Cheung, Sampayo-Escobar, Green, Moore, Mohapatra, Mohapatra: "Respiratory Syncytial Virus-Infected Mesenchymal Stem Cells Regulate Immunity via Interferon Beta and Indoleamine-2,3-Dioxygenase." in: PLoS ONE, Vol. 11, Issue 10, pp. e0163709, (2016) (PubMed).

Miles, Miller, Folkvord, Kimball, Chamanian, Meditz, Arends, McCarter, Levy, Rakasz, Skinner, Connick: "Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection." in: Nature communications, Vol. 6, pp. 8608, (2016) (PubMed).

Barathan, Gopal, Mohamed, Ellegård, Saeidi, Vadivelu, Ansari, Rothan, Ravishankar Ram, Zandi, Chang, Vignesh, Che, Kamarulzaman, Velu, Larsson, Kamarul, Shankar: "Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes." in: Apoptosis : an international journal on programmed cell death, (2015) (PubMed).

Gorchs, Hellevik, Bruun, Camilio, Al-Saad, Stuge, Martinez-Zubiaurre: "Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation." in: Frontiers in oncology, Vol. 5, pp. 87, (2015) (PubMed).

Bosnyák, Kamson, Guastella, Varadarajan, Robinette, Kupsky, Muzik, Michelhaugh, Mittal, Juhász: "Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas." in: Neuro-oncology, Vol. 17, Issue 9, pp. 1284-92, (2015) (PubMed).

Han, Chen, Yang, Jiang, Gu, Liu, Lin, Pan, Yu, Jiang, Zhou, Cao: "Human CD14+ CTLA-4+ regulatory dendritic cells suppress T-cell response by cytotoxic T-lymphocyte antigen-4-dependent IL-10 and indoleamine-2,3-dioxygenase production in hepatocellular carcinoma." in: Hepatology (Baltimore, Md.), Vol. 59, Issue 2, pp. 567-79, (2014) (PubMed).

Synonyme und alternative Namen zu IDO

indoleamine 2,3-dioxygenase 1 (IDO1), indoleamine 2,3-dioxygenase 1 (Ido1), IDO, Ido, IDO-1, INDO, Indo

Bezeichner auf Proteinebene für IDO

  • indolamine 2,3 dioxygenase
  • indole 2,3-dioxygenase
  • indoleamine-pyrrole 2,3-dioxygenase
  • IDO-1
  • indoleamine-pyrrole 2,3 dioxygenase
  • indoleamine 23-dioxygenase
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