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HYOU1 Produkte

(Hypoxia Up Regulated 1 (HYOU1))

Kategorien

The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. [provided by RefSeq, Oct 2008].

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Ausgewählte HYOU1 Kategorien

HYOU1 Antikörper

High quality antibodies with extensive validation data.

HYOU1 ELISA Kits

Reliable ELISA kits for a wide range of species.

HYOU1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene HYOU1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation IHC
Validierungen
  • (6)
Kat. Nr. ABIN7262503
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, ICC, IHC (p)
Validierungen
  • (8)
Kat. Nr. ABIN2855339
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (3)
  • (4)
Kat. Nr. ABIN564589
Menge 100 μg
Datenblatt Datenblatt

Empfohlene HYOU1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967510
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960602
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951267
Menge 96 tests
Datenblatt Datenblatt

Empfohlene HYOU1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1307312
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1307314
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1307316
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HYOU1 Produkten

Fauzia, Barbhuyan, Shrivastava, Kumar, Garg, Khan, Robertson, Raza: "Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism." in: Frontiers in pharmacology, Vol. 9, pp. 1034, (2018) (PubMed).

Du, Rong, Hui, Peng, Jin, Li, Wang, Li: "Expression and function of HSP110 family in mouse testis after vasectomy." in: Asian journal of andrology, Vol. 19, Issue 3, pp. 355-361, (2016) (PubMed).

Ruan, Huang, Jin, Chen, Li, Gong: "Tetrandrine attenuated cerebral ischemia/reperfusion injury and induced differential proteomic changes in a MCAO mice model using 2-D DIGE." in: Neurochemical research, Vol. 38, Issue 9, pp. 1871-9, (2013) (PubMed).

Yoshida, Yamashita, Nagano, Imai, Nabeshi, Yoshikawa, Yoshioka, Abe, Kamada, Tsutsumi, Tsunoda: "Limited expression of reticulocalbin-1 in lymphatic endothelial cells in lung tumor but not in normal lung." in: Biochemical and biophysical research communications, Vol. 405, Issue 4, pp. 610-4, (2011) (PubMed).

Liu, Li, Bai, Zhang, Tang, Lei, Chen, Liang, Zhao, Wei, Huang: "Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 1, pp. 70-85, (2009) (PubMed).

Lindenmeyer, Rastaldi, Ikehata, Neusser, Kretzler, Cohen, Schlöndorff: "Proteinuria and hyperglycemia induce endoplasmic reticulum stress." in: Journal of the American Society of Nephrology : JASN, Vol. 19, Issue 11, pp. 2225-36, (2008) (PubMed).

Synonyme und alternative Namen zu HYOU1

hypoxia up-regulated 1 (HYOU1), hypoxia up-regulated 1 (Hyou1), hypoxia up-regulated 1 (hyou1), hypoxia up-regulated protein 1 (LOC100380749), hypoxia up-regulated 1 S homeolog (hyou1.S), AI415631, Cab140, CBP-140, GRP-170, Grp170, GRP170, HSP12A, HYOU1, id:ibd5056, ORP-150, ORP150, Orp150, orp150, wu:fd14c05, zgc:56019

Bezeichner auf Proteinebene für HYOU1

  • 150 kDa oxygen-regulated protein
  • 170 kDa glucose-regulated protein
  • glucose-regulated protein 170
  • hypoxia up-regulated protein 1
  • oxygen regulated protein (150kD)
  • 140 kDa Ca(2+)-binding protein
  • 150-kDa oxygen regulated protein
  • 170 kDa glucose regulated protein GRP170
  • GRP-170
  • calcium binding protein 140
  • calcium binding protein, 140 kDa
  • ORP-150
  • hypoxia up-regulated 1
  • Hypoxia up-regulated protein 1
  • hypoxia up-regulated protein 1-like
  • glucose regulated protein, 170 kDa
  • oxygen regulated protein, 150 kDa
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