HGF Proteine
(Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
| Catalog no. | Produkt | Reaktivität | Wirt / Klonalität | Anwendung | Preis & Lieferzeit |
|---|---|---|---|---|---|
| HGF Protein (AA 495-719) (His tag) | Maus | Bacteria |
|
302,50 €
Preis anzeigen
|
|
| HGF Protein (AA 28-209) (His tag) | Human | Bacteria |
|
302,50 €
Preis anzeigen
|
|
| HGF Protein (AA 32-728) | Human | Mammalian Cells |
|
184,80 €
Preis anzeigen
|
|
| HGF Protein (AA 32-494, AA 495-728) | Human | Insektenzellen |
|
252,35 €
Preis anzeigen
|
|
| HGF Protein (DYKDDDDK Tag) | Human | HEK-293 Cells |
|
620,00 €
Preis anzeigen
|
|
| HGF Protein | Human | CHO Cells |
|
9.078,93 €
Preis anzeigen
|
|
| HGF Protein (Chain B) | Human | – |
|
7.296,93 €
Preis anzeigen
|
|
| HGF Protein (Chain A) | Human | – |
|
7.296,93 €
Preis anzeigen
|
|
| HGF Protein (His tag) | Human | Escherichia coli (E. coli) |
|
503,00 €
Preis anzeigen
|
|
| HGF Protein (His tag) | Human | Mammalian Cells |
|
730,00 €
Preis anzeigen
|
|
| HGF Protein (His tag) | Maus | Escherichia coli (E. coli) |
|
503,00 €
Preis anzeigen
|
|
| HGF Protein (His tag) | Rind (Kuh) | Escherichia coli (E. coli) |
|
628,83 €
Preis anzeigen
|
Produktnummer ABIN7820040
302,50 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 4 bis 5 Werktagen
Produktnummer ABIN7816787
302,50 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 4 bis 5 Werktagen
Protein
- Func (Functional Studies: Angegebene Anwendung)
- Spezies
- Human
- Wirt
- Mammalian Cells
- Protein-Typ
- Recombinant
- Reinheit
- >95 % as determined by SDS-PAGE.
- Biologische Aktivität
- Active
Produktnummer ABIN2816837
184,80 €
Zzgl. Versandkosten 20,00 € und MwSt
2 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 11 bis 15 Werktagen
Protein
- FACS (Flow Cytometry: Angegebene Anwendung)
- Spezies
- Human
- Wirt
- Insektenzellen
- Protein-Typ
- Recombinant
- Reinheit
- > 98 % , as determined by Coomassie stained SDS-PAGE and HPLC analysis.
- Biologische Aktivität
- Active
Produktnummer ABIN2666488
252,35 €
Zzgl. Versandkosten 20,00 € und MwSt
10 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 6 bis 8 Werktagen
Protein
- Spezies
- Human
- Wirt
- HEK-293 Cells
- Protein-Typ
- Recombinant
- Reinheit
- The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7794648
620,00 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
Lieferung nach:
Deutschland
Lieferung in 6 bis 9 Werktagen
Produktnummer ABIN1064048
9.078,93 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 10 bis 12 Werktagen
Produktnummer ABIN1064051
7.296,93 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 10 bis 12 Werktagen
Produktnummer ABIN1064050
7.296,93 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 10 bis 12 Werktagen
Protein
- WB (Western Blotting: Angegebene Anwendung)
- SDS (SDS-PAGE: Angegebene Anwendung)
- Imm (Immunogen: Angegebene Anwendung)
- ELISA (ELISA: Angegebene Anwendung)
- Spezies
- Human
- Wirt
- Escherichia coli (E. coli)
- Protein-Typ
- Recombinant
Produktnummer ABIN7941783
503,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 12 bis 17 Werktagen
Protein
- WB (Western Blotting: Angegebene Anwendung)
- SDS (SDS-PAGE: Angegebene Anwendung)
- Imm (Immunogen: Angegebene Anwendung)
- ELISA (ELISA: Angegebene Anwendung)
- Spezies
- Human
- Wirt
- Mammalian Cells
- Protein-Typ
- Recombinant
Produktnummer ABIN7941785
730,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 12 bis 17 Werktagen
Protein
- WB (Western Blotting: Angegebene Anwendung)
- SDS (SDS-PAGE: Angegebene Anwendung)
- Imm (Immunogen: Angegebene Anwendung)
- ELISA (ELISA: Angegebene Anwendung)
- Spezies
- Maus
- Wirt
- Escherichia coli (E. coli)
- Protein-Typ
- Recombinant
Produktnummer ABIN7949149
503,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 12 bis 17 Werktagen
Protein
- WB (Western Blotting: Angegebene Anwendung)
- SDS (SDS-PAGE: Angegebene Anwendung)
- Spezies
- Rind (Kuh)
- Wirt
- Escherichia coli (E. coli)
- Protein-Typ
- Recombinant
- Reinheit
- > 90 %
Produktnummer ABIN6123450
628,83 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 7 bis 15 Werktagen
Aktuelle Publikationen für unsere HGF Proteine
: "Chidamide increases the sensitivity of Non-small Cell Lung Cancer to Crizotinib by decreasing c-MET mRNA methylation." in: International journal of biological sciences, Vol. 16, Issue 14, pp. 2595-2611, (2020) (PubMed).
: "Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway." in: Oncogene, (2016) (PubMed).
: "Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy." in: Diabetes, Vol. 64, Issue 7, pp. 2581-92, (2015) (PubMed).
: "Endothelial Cells Derived from Non-malignant Tissues Are of Limited Value as Models for Brain Tumor Vasculature." in: Anticancer research, Vol. 35, Issue 5, pp. 2681-90, (2015) (PubMed).
: "PAX2 promoted prostate cancer cell invasion through transcriptional regulation of HGF in an in vitro model." in: Biochimica et biophysica acta, Vol. 1852, Issue 11, pp. 2467-73, (2015) (PubMed).
: "Heat-shock protein 27 (HSP27, HSPB1) is up-regulated by MET kinase inhibitors and confers resistance to MET-targeted therapy." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 9, pp. 4055-67, (2015) (PubMed).
: "Primary structure of rat hepatocyte growth factor and induction of its mRNA during liver regeneration following hepatic injury." in: European journal of biochemistry / FEBS, Vol. 193, Issue 2, pp. 375-81, (1990) (PubMed).
: "Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 8, pp. 3200-4, (1990) (PubMed).
: "Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway." in: Oncogene, (2016) (PubMed).
: "Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy." in: Diabetes, Vol. 64, Issue 7, pp. 2581-92, (2015) (PubMed).
: "Endothelial Cells Derived from Non-malignant Tissues Are of Limited Value as Models for Brain Tumor Vasculature." in: Anticancer research, Vol. 35, Issue 5, pp. 2681-90, (2015) (PubMed).
: "PAX2 promoted prostate cancer cell invasion through transcriptional regulation of HGF in an in vitro model." in: Biochimica et biophysica acta, Vol. 1852, Issue 11, pp. 2467-73, (2015) (PubMed).
: "Heat-shock protein 27 (HSP27, HSPB1) is up-regulated by MET kinase inhibitors and confers resistance to MET-targeted therapy." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 9, pp. 4055-67, (2015) (PubMed).
: "Primary structure of rat hepatocyte growth factor and induction of its mRNA during liver regeneration following hepatic injury." in: European journal of biochemistry / FEBS, Vol. 193, Issue 2, pp. 375-81, (1990) (PubMed).
: "Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 8, pp. 3200-4, (1990) (PubMed).
Aliase für HGF Proteine
hepatocyte growth factor (HGF) Proteinehepatocyte growth factor (Hgf) Proteine
C230052L06Rik Proteine
DFNB39 Proteine
F-TCF Proteine
HGF Proteine
HGF/SF Proteine
HGFB Proteine
HPTA Proteine
NK1 Proteine
NK2 Proteine
SF Proteine
SF/HGF Proteine
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