anti-Tripartite Motif Containing 28 (TRIM28) Antikörper

Bezeichnung:: anti-Tripartite Motif Containing 28 Antikörper (TRIM28)

Auf www.antikoerper-online.de finden Sie aktuell 234 Tripartite Motif Containing 28 (TRIM28) Antikörper von 34 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Tripartite Motif Containing 28 Proteine (15) und Tripartite Motif Containing 28 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 263 Tripartite Motif Containing 28 Produkte verfügbar.

Synonyme:: AA408787, KAP-1, Kap1, KRIP-1, Krip1, rnf96, tf1b, Tif1b, TIF1BETA, TRIM28

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	TRIM28	10155	Q13263
	TRIM28	21849	Q62318
	TRIM28	116698	O08629
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Am meisten referenzierte anti-Tripartite Motif Containing 28 Antikörper

Human Polyclonal TRIM28 Primary Antibody für ICC, IF - ABIN250742 : Biton, Gropp, Itsykson, Pereg, Mittelman, Johe, Reubinoff, Shiloh: ATM-mediated response to DNA double strand breaks in human neurons derived from stem cells. in DNA repair 2007 (PubMed)
Show all 29 Pubmed References
Human Polyclonal TRIM28 Primary Antibody für ICC, IF - ABIN152978 : Yang, OHerrin, Wu, Reagan-Shaw, Ma, Bhat, Gravekamp, Setaluri, Peters, Hoffmann, Peng, Ivanov, Simpson, Longley: MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines. in Cancer research 2007 (PubMed)
Show all 14 Pubmed References
Human Polyclonal TRIM28 Primary Antibody für WB - ABIN2801954 : Solberg, Taskén, Keiserud, Jahnsen: Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases. in Biochemical and biophysical research communications 1991 (PubMed)
Show all 5 Pubmed References
Human Polyclonal TRIM28 Primary Antibody für ELISA, ICC - ABIN249751 : Yokoe, Toiyama, Okugawa, Tanaka, Ohi, Inoue, Mohri, Miki, Kusunoki: KAP1 is associated with peritoneal carcinomatosis in gastric cancer. in Annals of surgical oncology 2010 (PubMed)
Show all 3 Pubmed References
Human Monoclonal TRIM28 Primary Antibody für ChIP, ICC - ABIN2668932 : Riclet, Chendeb, Vonesch, Koczan, Thiesen, Losson, Cammas et al.: Disruption of the interaction between transcriptional intermediary factor 1{beta} and heterochromatin protein 1 leads to a switch from DNA hyper- to hypomethylation and H3K9 to H3K27 trimethylation ... in Molecular biology of the cell 2009 (PubMed)
Show all 2 Pubmed References
Human Polyclonal TRIM28 Primary Antibody für IHC, ELISA - ABIN184913 : Friedman, Fredericks, Jensen, Speicher, Huang, Neilson, Rauscher: KAP-1, a novel corepressor for the highly conserved KRAB repression domain. in Genes & development 1996 (PubMed)
Show all 2 Pubmed References
Human Monoclonal TRIM28 Primary Antibody für IF, IHC (p) - ABIN564395 : Dihazi, Dihazi, Jahn, Meyer, Nolte, Asif, Mueller, Engel: Multipotent adult germline stem cells and embryonic stem cells functional proteomics revealed an important role of eukaryotic initiation factor 5A (Eif5a) in stem cell differentiation. in Journal of proteome research 2011 (PubMed)
Human Polyclonal TRIM28 Primary Antibody für IF (p), IHC (p) - ABIN746108 : Ding, Zhang, Wang, Wang, Fan, He, Zhang, Gao, Li, Chen: γ-H2AX/53BP1/pKAP-1 foci and their linear tracks induced by in vitro exposure to radon and its progeny in human peripheral blood lymphocytes. in Scientific reports 2016 (PubMed)
Human Polyclonal TRIM28 Primary Antibody für ICC, IF - ABIN152979 : Roset, Inagaki, Hohl, Brenet, Lafrance-Vanasse, Lange, Scandura, Tainer, Keeney, Petrini: The Rad50 hook domain regulates DNA damage signaling and tumorigenesis. in Genes & development 2014 (PubMed)

Weitere Antikörper gegen Tripartite Motif Containing 28 Interaktionspartner

Human Tripartite Motif Containing 28 (TRIM28) Interaktionspartner

Authors identify a viral mechanism for the counteraction of KAP1 (zeige CDKN3 Antikörper) in which interference with the KAP1 (zeige CDKN3 Antikörper) phosphatase protein phosphatase 1 (zeige PPP1CB Antikörper) (PP1 (zeige PPA1 Antikörper)) by the AAV2 Rep proteins mediates enhanced phosphorylation of KAP1 (zeige CDKN3 Antikörper)-S824 and thus relief from KAP1 (zeige CDKN3 Antikörper) repression.
Evaluation of the potential mechanism demonstrated that TRIM28 promoted cervical cancer cell growth by activating the mammalian target of rapamycin (mTOR (zeige FRAP1 Antikörper)) signaling pathway. In support of this finding, TRIM28-induced cell proliferation was abolished by treatment with everolimus, a specific mTOR (zeige FRAP1 Antikörper) inhibitor
TRIM28 employs KRAB-ZNFs to evoke epigenetic silencing of its target differentiation genes via H3K9me3 and DNA methylation (zeige HELLS Antikörper).
Study describes germline mutations and loss of function of TRIM28 in familial Wilms tumours, along with somatic loss of function in a non-familial Wilms tumour. Inactivation of TRIM28 provides the molecular basis for defining a previously described subtype of Wilms tumour, that has early age of onset and excellent prognosis.
Study identified TRIM28 among REST-interacting proteins, and suggested functional links between REST and TRIM28 during neuronal development and differentiation via induction of CTNND2 (zeige CTNND2 Antikörper) expression.
Data indicate a mechanism in breast cancer cells that tripartite motif-containing 28 protein (TRIM28) enhances metastasis by stabilizing TWIST1 (zeige TWIST1 Antikörper), suggesting that targeting TRIM28 could be an efficacious strategy in breast cancer treatment.
Gamma-H2AX (zeige H2AFX Antikörper), phosphorylated KAP-1 (zeige CDKN3 Antikörper) and 53BP1 (zeige TP53BP1 Antikörper) play an important role in the repair of heterochromatic radon-induced DNA double-strand breaks.
Our data demonstrate that the downregulation of TRIM28 gene expression reduced the ability of CSCs to self-renew that resulted in significant reduction of tumor growth. Loss of function of TRIM28 leads to dysregulation of cell cycle, cellular response to stress, cancer cell metabolism, and inhibition of oxidative phosphorylation.
Cell proliferation and apoptosis were almost completely abolished in the PAa cells cotreated with TRIM28 siRNA and etoposide following knockdown of E2F1 (zeige E2F1 Antikörper). The results of our study demonstrated that the combination of TRIM28 siRNA and etoposide may be effective against nonsmall cell lung cancer (NSCLC)and has the potential of being a new therapeutic tool for future treatment.
The authors found that TRIM28 regulates alpha-Synuclein and tau nuclear levels and that its reduction rescues toxicity in animal models of tau- and alpha-Synuclein-mediated degeneration.

Mouse (Murine) Tripartite Motif Containing 28 (TRIM28) Interaktionspartner

regulation of epigenetic modifications coordinated by TRIM28 plays a crucial role in reprogramming process.
The interaction of repressor proteins Trim28 and YY1 (zeige YY1 Antikörper) are involved in the silencing of Moloney murine leukemia virus.
an important role for TRIM28 in cells resisting transition between somatic and pluripotent states, is reported.
Nuclear factors that bind to genomic regions with "Sertoli Cell Signature" could functionally interact with SOX9 (zeige SOX9 Antikörper); TRIM28 is a new SOX9 (zeige SOX9 Antikörper) partner in fetal testes.
TRIM28 safeguards germline-to-soma inheritance of epigenetic features at other genomic regions in an exquisitely stage-dependent manner.
Data suggest that TRIM28 regulates the expression of a subset of lncRNAs.
Zygotic TRIM28 is essential for genomic imprinting. Secondary imprints were hypomethylated in TRIM28 mutants.
Trim28(+/D9) mutant mice exhibit a bi-modal body-weight distribution, with isogenic animals randomly emerging as either normal or obese and few intermediates.
Data suggest that interaction between KAP1 and the KRAB A (zeige ZNF223 Antikörper) box of zinc finger protein 809 (ZFP809) is critical in KAP1-dependent control of gene silencing for ZFP809 targets.
We find that NPCs use TRIM28-mediated histone modifications to dynamically regulate transcription and silencing of ERVs, which is in contrast to other somatic cell types using DNA methylation (zeige HELLS Antikörper)

Cow (Bovine) Tripartite Motif Containing 28 (TRIM28) Interaktionspartner

Nuclear factors that bind to genomic regions with "Sertoli Cell Signature" could functionally interact with SOX9 (zeige SOX9 Antikörper); TRIM28 is a new SOX9 (zeige SOX9 Antikörper) partner in fetal testes.

Tripartite Motif Containing 28 (TRIM28) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.

Alternative names and synonyms associated with Tripartite Motif Containing 28 (TRIM28)

tripartite motif containing 28 (TRIM28) Antikörper
tripartite motif containing 28 L homeolog (trim28.L) Antikörper
tripartite motif-containing 28 (Trim28) Antikörper
tripartite motif containing 28 (Trim28) Antikörper

AA408787 Antikörper
KAP-1 Antikörper
Kap1 Antikörper
KRIP-1 Antikörper
Krip1 Antikörper
rnf96 Antikörper
tf1b Antikörper
Tif1b Antikörper
TIF1BETA Antikörper
TRIM28 Antikörper

Bezeichner auf Proteinebene für TRIM28

E3 SUMO-protein ligase TRIM28 , KAP-1 , KRAB-associated protein 1 , KRAB-interacting protein 1 , KRIP-1 , RING finger protein 96 , TIF1-beta , nuclear corepressor KAP-1 , transcription intermediary factor 1-beta , transcriptional intermediary factor 1-beta , tripartite motif-containing 28 , tripartite motif-containing protein 28 , transcription intermediary factor 1-beta-like , KRAB-A-interacting protein , transcriptional intermediary factor 1, beta , tripartite motif protein 28 , TIF1beta transcription factor

GENE ID	SPEZIES
10155	Homo sapiens
430538	Gallus gallus
711982	Macaca mulatta
734995	Xenopus laevis
100395205	Callithrix jacchus
100484385	Ailuropoda melanoleuca
21849	Mus musculus
116698	Rattus norvegicus
403689	Canis lupus familiaris
519422	Bos taurus
100717540	Cavia porcellus

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