(Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012].
Crane, Han, Ahn, Oehlke, Kivett, Fedoroff, Butowski, Chang, Clarke, Berger, McDermott, Prados, Parsa: "Individual patient-specific immunity against high-grade glioma after vaccination with autologous tumor derived peptides bound to the 96 KD chaperone protein." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 1, pp. 205-14, (2013) (PubMed).
Aliase für GRP94 Proteine
heat shock protein 90kDa beta (Grp94), member 1 (hsp90b1) Proteine heat shock protein Hsp90 family protein (grp94) Proteine 94 kD glucose-regulated protein (grp94) Proteine heat shock protein 90 beta family member 1 (HSP90B1) Proteine heat shock protein 90, beta (Grp94), member 1 (Hsp90b1) Proteine heat shock protein 90, beta (grp94), member 1 (hsp90b1) Proteine heat shock protein 90 beta family member 1 (Hsp90b1) Proteine heat shock protein 90kDa beta family member 1 L homeolog (hsp90b1.L) Proteine heat shock protein 90kDa beta (Grp94), member 1 (HSP90B1) Proteine DDBDRAFT_0206450 Proteine DDBDRAFT_0215015 Proteine DDB_0206450 Proteine DDB_0215015 Proteine ecgp Proteine ECGP Proteine endoplasmin Proteine ERp99 Proteine fb61d09 Proteine gp96 Proteine GP96 Proteine Gp96 Proteine grp94 Proteine GRP94 Proteine Grp94 Proteine HSP90B1 Proteine hsp108 Proteine ppk98 Proteine TA-3 Proteine Targ2 Proteine Tra-1 Proteine tra-1 Proteine tra1 Proteine TRA1 Proteine Tra1 Proteine wu:fb61d09 Proteine wu:fq25g01 Proteine