GRM2 Produkte
(Glutamate Receptor, Metabotropic 2 (GRM2))
Kategorien
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte GRM2 Kategorien
GRM2 Antikörper
High quality antibodies with extensive validation data.
GRM2 ELISA Kits
Reliable ELISA kits for a wide range of species.
GRM2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GRM2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IHC, ICC, FACS, Neut
Validierungen
- (4)
Kat. Nr.
ABIN5611158
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Bat, Cow, Dog, Hamster, Human, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC, IHC (p), ICC
Validierungen
- (3)
Kat. Nr.
ABIN1048929
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human, Monkey, Rabbit
Applikation
IHC, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN213522
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene GRM2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1743299
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Validierungen
Kat. Nr.
ABIN1774204
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1744518
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GRM2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355778
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3081168
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3121631
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GRM2 Produkten
: "Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 1, pp. 103-13, (2009) (PubMed).: "Glial proliferation and metabotropic glutamate receptor expression in amyotrophic lateral sclerosis." in: Journal of neuropathology and experimental neurology, Vol. 63, Issue 8, pp. 831-40, (2004) (PubMed).
: "The metabotropic glutamate receptor 5 is necessary for late-phase long-term potentiation in the hippocampal CA1 region." in: Brain research, Vol. 1022, Issue 1-2, pp. 12-8, (2004) (PubMed).
: "Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 40, pp. 8752-61, (2004) (PubMed).
: "Control of kinetic properties of GluR2 flop AMPA-type channels: impact of R/G nuclear editing." in: The European journal of neuroscience, Vol. 15, Issue 1, pp. 51-62, (2002) (PubMed).
: "Presynaptic group II metabotropic glutamate receptors reduce stimulated and spontaneous transmitter release in human dentate gyrus." in: Neuropharmacology, Vol. 42, Issue 3, pp. 297-305, (2002) (PubMed).
: "Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses." in: Nature, Vol. 410, Issue 6828, pp. 588-92, (2001) (PubMed).
Synonyme und alternative Namen zu GRM2
glutamate metabotropic receptor 2 (GRM2), glutamate receptor, metabotropic 2 (Grm2), glutamate metabotropic receptor 2 (Grm2), 4930441L02Rik, GLUR2, GPRC1B, Gprc1b, mGlu2, MGLUR2, mGluR2, mGluR7Bezeichner auf Proteinebene für GRM2
- glutamate metabotropic receptor 2
- glutamate receptor homolog
- metabotropic glutamate receptor 2
- G protein coupled receptor, family C, group 1, member B
- G protein-coupled receptor, family C, group 1, member B
- mGluR2
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