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GREM1 Proteine

(Gremlin 1 (GREM1))
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

26 Treffer

GREM1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB, ELISA Active
Produktnummer ABIN5608258
 
GREM1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB, ELISA Active
Produktnummer ABIN5608259
 
GREM1 Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7584561
 
GREM1 Spezies: Xenopus laevis Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN1511647
 
GREM1 Spezies: Rhesusaffen Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN1640173
 
GREM1 Spezies: Huhn Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN1459332
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Functional Studies (Func)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Cell Culture (CC)
    • Antibody Production (AbP)
    • Immunoprecipitation (IP)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reaktivität
    • Human
    • Rat
    • Chicken
    • Mouse
    • Rhesus Monkey
    • Xenopus laevis
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • CHO Cells
    • Wheat germ
    • Mammalian Cells
  • Bindungsspezifität
    • AA 25-184
    • AA 26-184
    • partial
    • AA 1-184
    • AA 25-124
    • AA 25-182
    • AA 27-184
    • Transcript Variant 1
  • Konjugat
    • His tag
    • Unkonjugiert
    • Fc Tag
    • GST tag
    • His-IF2DI Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Hersteller
    • antibodies-online
    • CUSABIO
    • Abbexa
    • ProSci
    • ACROBiosystems
    • Cloud-Clone
    • OriGene

Aktuelle Publikationen für unsere GREM1 Proteine

Kim, Sung, Youn, Park: "Gremlin-1 activates Akt/STAT3 signaling, which increases the glycolysis rate in breast cancer cells." in: Biochemical and biophysical research communications, Vol. 533, Issue 4, pp. 1378-1384, (2020) (PubMed).

Aliase für GREM1 Proteine

gremlin 1a, DAN family BMP antagonist (grem1a) Proteine
gremlin 1, DAN family BMP antagonist (GREM1) Proteine
gremlin 1 (LOC662541) Proteine
gremlin 1, DAN family BMP antagonist (grem1) Proteine
gremlin 1, DAN family BMP antagonist (Grem1) Proteine
gremlin 1, DAN family BMP antagonist L homeolog (grem1.L) Proteine
Cktsf1b1 Proteine
CKTSF1B1 Proteine
cktsf1b1 Proteine
dand2 Proteine
DAND2 Proteine
drm Proteine
Drm Proteine
DRM Proteine
Grem Proteine
grem1 Proteine
GREM1 Proteine
gremlin Proteine
GREMLIN Proteine
gremlin-1 Proteine
ihg-2 Proteine
IHG-2 Proteine
ld Proteine
MGC136702 Proteine
pig2 Proteine
zgc:136702 Proteine
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