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GPBAR1 Produkte

(G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].

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Ausgewählte GPBAR1 Kategorien

GPBAR1 Antikörper

High quality antibodies with extensive validation data.

GPBAR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

GPBAR1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GPBAR1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN7153307
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC (p), WB
Validierungen
  • (3)
Kat. Nr. ABIN2857020
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN1049401
Menge 50 μg
Datenblatt Datenblatt

Empfohlene GPBAR1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966916
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956015
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6973446
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GPBAR1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3104305
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3124225
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1355520
Menge 2 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GPBAR1 Produkten

Mikó, Vida, Kovács, Ujlaki, Trencsényi, Márton, Sári, Kovács, Boratkó, Hujber, Csonka, Antal-Szalmás, Watanabe, Gombos, Csoka, Kiss, Vígh, Szabó, Méhes, Sebestyén, Goedert, Bai: "Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness." in: Biochimica et biophysica acta. Bioenergetics, Vol. 1859, Issue 9, pp. 958-974, (2018) (PubMed).

Kim, Park, Lee, Rhyu, Kim: "Ginsenoside metabolite compound K stimulates glucagon-like peptide-1 secretion in NCI-H716 cells via bile acid receptor activation." in: Archives of pharmacal research, Vol. 37, Issue 9, pp. 1193-200, (2014) (PubMed).

Kim, Lee, Rhyu, Kim: "Spergularia marina induces glucagon-like peptide-1 secretion in NCI-H716 cells through bile acid receptor activation." in: Journal of medicinal food, Vol. 17, Issue 11, pp. 1197-203, (2014) (PubMed).

Yoneno, Hisamatsu, Shimamura, Kamada, Ichikawa, Kitazume, Mori, Uo, Namikawa, Matsuoka, Sato, Koganei, Sugita, Kanai, Hibi: "TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease." in: Immunology, Vol. 139, Issue 1, pp. 19-29, (2013) (PubMed).

Ockenga, Valentini, Schuetz, Wohlgemuth, Glaeser, Omar, Kasim, duPlessis, Featherstone, Davis, Tietge, Kroencke, Biebermann, Köhrle, Brabant: "Plasma bile acids are associated with energy expenditure and thyroid function in humans." in: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 2, pp. 535-42, (2012) (PubMed).

Cipriani, Mencarelli, Bruno, Renga, Distrutti, Santucci, Baldelli, Fiorucci: "Activation of the bile acid receptor GPBAR1 protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs and aspirin in mice." in: British journal of pharmacology, Vol. 168, Issue 1, pp. 225-37, (2012) (PubMed).

Alemi, Poole, Chiu, Schoonjans, Cattaruzza, Grider, Bunnett, Corvera: "The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice." in: Gastroenterology, Vol. 144, Issue 1, pp. 145-54, (2012) (PubMed).

Cipriani, Mencarelli, Chini, Distrutti, Renga, Bifulco, Baldelli, Donini, Fiorucci: "The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis." in: PLoS ONE, Vol. 6, Issue 10, pp. e25637, (2011) (PubMed).

Synonyme und alternative Namen zu GPBAR1

G protein-coupled bile acid receptor 1 (GPBAR1), G protein-coupled bile acid receptor 1 (Gpbar1), G protein-coupled bile acid receptor 1 S homeolog (gpbar1.S), BG37, GPBAR1, Gpbar1, GPCR, GPCR19, GPR131, M-BAR, MGC84403, TGR5, Tgr5

Bezeichner auf Proteinebene für GPBAR1

  • G-protein coupled bile acid receptor 1
  • G-protein coupled bile acid receptor BG37
  • G-protein coupled receptor GPCR19
  • hBG37
  • hGPCR19
  • membrane bile acid receptor
  • membrane-type receptor for bile acids
  • G protein-coupled receptor TGR5
  • G protein-coupled receptor
  • M-BAR
  • G protein-coupled bile acid receptor 1
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