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GP5 Produkte

(Glycoprotein V (Platelet) (GP5))

Kategorien

Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998

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Ausgewählte GP5 Kategorien

GP5 Antikörper

High quality antibodies with extensive validation data.

GP5 ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene GP5 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, IHC (p), WB
Validierungen
  • (2)
Kat. Nr. ABIN3181433
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB
Validierungen
  • (1)
Kat. Nr. ABIN7186233
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation FACS
Validierungen
  • (1)
Kat. Nr. ABIN476829
Menge 100 μg
Datenblatt Datenblatt

Empfohlene GP5 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967156
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960663
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1115221
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GP5 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3080931
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3131301
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3113548
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GP5 Produkten

Sato, Kiyokawa, Takada, Itagaki, Saito, Sekino, Suzuki, Taguchi, Mimori, Lanza, Fujimoto: "Characterization of monoclonal antibodies against mouse and rat platelet glycoprotein V (CD42d)." in: Hybridoma, Vol. 19, Issue 6, pp. 455-61, (2001) (PubMed).

Sato, Kiyokawa, Taguchi, Suzuki, Sekino, Ohmi, Itagaki, Sato, Lepage, Lanza, Fujimoto: "Functional conservation of platelet glycoprotein V promoter between mouse and human megakaryocytes." in: Experimental hematology, Vol. 28, Issue 7, pp. 802-14, (2000) (PubMed).

Ravanat, Morales, Azorsa, Moog, Schuhler, Grunert, Loew, Van Dorsselaer, Cazenave, Lanza: "Gene cloning of rat and mouse platelet glycoprotein V: identification of megakaryocyte-specific promoters and demonstration of functional thrombin cleavage." in: Blood, Vol. 89, Issue 9, pp. 3253-62, (1997) (PubMed).

Takada, Saito, Kaneko, Iizuka, Kokai, Fujimoto: "Novel monoclonal antibody reactive with thrombin-sensitive 74-kDa glycoproteins present on platelets and megakaryocytes both from mouse and rat." in: Hybridoma, Vol. 14, Issue 4, pp. 361-7, (1996) (PubMed).

Modderman, Admiraal, Sonnenberg, von dem Borne: "Glycoproteins V and Ib-IX form a noncovalent complex in the platelet membrane." in: The Journal of biological chemistry, Vol. 267, Issue 1, pp. 364-9, (1992) (PubMed).

Synonyme und alternative Namen zu GP5

glycoprotein V platelet L homeolog (gp5.L), glycoprotein V platelet (GP5), glycoprotein 5 (platelet) (Gp5), glycoprotein V (platelet) (Gp5), glycoprotein V platelet (Gp5), glycoprotein V (platelet) (GP5), CD42d, GPV, lib, PLGPV

Bezeichner auf Proteinebene für GP5

  • glycoprotein 5 (platelet)
  • platelet glycoprotein V
  • glycoprotein V (platelet)
  • platelet glycoprotein V-like
  • GPV
  • Platelet glycoprotein 5
  • Platelete glycoprotein 5
  • glycoprotein 5, platelet
  • glycoprotein 5
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