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FURIN Produkte

(Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can efficiently cleave precursor proteins at their paired basic amino acid processing sites. Some of its substrates are: proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene is thought to play a role in tumor progression. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte FURIN Kategorien

FURIN Antikörper

High quality antibodies with extensive validation data.

FURIN ELISA Kits

Reliable ELISA kits for a wide range of species.

FURIN Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FURIN Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
anti-FURIN Antikörper (AA 120-370)
Reaktivität Human
Applikation WB, IHC, IP, IF
Validierungen
  • (6)
Kat. Nr. ABIN6140815
Menge 100 μL
Datenblatt Datenblatt
anti-FURIN Antikörper (AA 587-748)
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7442045
Menge 100 μL
Datenblatt Datenblatt
anti-FURIN Antikörper (AA 418-573)
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7437320
Menge 100 μL
Datenblatt Datenblatt

Empfohlene FURIN ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
FURIN ELISA Kit
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN6574306
Menge 96 tests
Datenblatt Datenblatt
FURIN ELISA Kit
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966913
Menge 96 tests
Datenblatt Datenblatt
FURIN ELISA Kit
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966912
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FURIN Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
FURIN Protein (AA 28-794) (GST tag)
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1354517
Menge 10 μg
Datenblatt Datenblatt
FURIN Protein (AA 108-371) (His-IF2DI Tag)
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7123019
Menge 50 μg
Datenblatt Datenblatt
FURIN Protein (AA 1-148)
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN934971
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FURIN Produkten

Leng, Akther, Hackstein, Powell, King, Friedrich, Christoforidou, McCuaig, Neyazi, Arancibia-Cárcamo, Hagel, Powrie, Peres, Millar, Ebner, Lamichhane, Ussher, Hinks, Marchi, Willberg, Klenerman: "TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions." in: Cell reports, Vol. 28, Issue 12, pp. 3077-3091.e5, (2019) (PubMed).

Choucry, Al-Shorbagy, Attia, El-Abhar: "Pharmacological Manipulation of Trk, p75NTR, and NGF Balance Restores Memory Deficit in Global Ischemia/Reperfusion Model in Rats." in: Journal of molecular neuroscience : MN, Vol. 68, Issue 1, pp. 78-90, (2019) (PubMed).

Roveri, Pfohl, Jaaks, Alijaj, Leroux, Luciani, Bernasconi: "Prolonged circulation and increased tumor accumulation of liposomal vincristine in a mouse model of rhabdomyosarcoma." in: Nanomedicine (London, England), Vol. 12, Issue 10, pp. 1135-1151, (2017) (PubMed).

Wu, Ding, Han, Arriens, Wei, Han, Pedroza, Jiang, Anolik, Petri, Sanz, Saxena, Mohan: "Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study." in: Journal of proteome research, Vol. 15, Issue 7, pp. 2102-14, (2016) (PubMed).

Heng, Dynon, Li, Edgell, Walton, Rombauts, Vollenhoven, Nie: "Development of a high-throughput assay for human proprotein convertase 5/6 for detecting uterine receptivity." in: Analytical biochemistry, Vol. 475, pp. 14-21, (2015) (PubMed).

Fathy, Abdel Hamid, Zabut, Jamee, Ali, Abu Mustafa: "Diagnostic utility of BNP, corin and furin as biomarkers for cardiovascular complications in type 2 diabetes mellitus patients." in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 20, Issue 6-7, pp. 460-9, (2015) (PubMed).

Wu, Hsu, Chiu, Chen, Ni, Chang: "The effects of cytokines on spontaneous hepatitis B surface antigen seroconversion in chronic hepatitis B virus infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 2, pp. 690-6, (2015) (PubMed).

Harihar, Pounds, Iwakuma, Seidah, Welch: "Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing." in: PLoS ONE, Vol. 9, Issue 1, pp. e84958, (2014) (PubMed).

Kabeiseman, Cichos, Moore: "The eukaryotic signal sequence, YGRL, targets the chlamydial inclusion." in: Frontiers in cellular and infection microbiology, Vol. 4, pp. 129, (2014) (PubMed).

Ennemann, Radhakrishnan, Mariappan, Wachs, Pringle, Schmidt, Dierks: "Proprotein convertases process and thereby inactivate formylglycine-generating enzyme." in: The Journal of biological chemistry, Vol. 288, Issue 8, pp. 5828-39, (2013) (PubMed).

Synonyme und alternative Namen zu FURIN

furin, paired basic amino acid cleaving enzyme (FURIN), furin (paired basic amino acid cleaving enzyme) a (furina), furin (paired basic amino acid cleaving enzyme) b (furinb), furin, paired basic amino acid cleaving enzyme (furin), furin, paired basic amino acid cleaving enzyme L homeolog (furin.L), furin (paired basic amino acid cleaving enzyme) (Furin), 9130404I01Rik, FUR, Fur, FURIN, furin, LOC100220259, MGC82710, PACE, Pace, PCSK3, Pcsk3, si:dkey-281a24.5, spc1, SPC1, xfurin

Bezeichner auf Proteinebene für FURIN

  • furin (paired basic amino acid cleaving enzyme)
  • furin A
  • stu
  • sturgeon
  • furin B
  • furin
  • furin-like
  • FES upstream region
  • dibasic processing enzyme
  • dibasic-processing enzyme
  • furin, membrane associated receptor protein
  • paired basic amino acid residue-cleaving enzyme
  • proprotein convertase subtilisin/kexin type 3
  • paired basic amino acid residue cleaving enzyme
  • prohormone convertase 3
  • subtilisin pro-protein processing enzyme
  • paired basic amino acid cleaving enzyme
  • trans Golgi network protease furin
  • Paired basic amino acid cleaving enzyme (furin)
  • Proprotein convertase subtilisin/kexin type 3 (paired basic amino acid cleaving enzyme, furin, membrane associated receptor protein)
  • proprotein convertase subtilisin/kexin type3

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