This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
custom-made
FTH1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
FTH1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
FTH1
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Produktnummer ABIN3132682
ab
15.754,29 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
custom-made
FTH1
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Produktnummer ABIN3080261
ab
15.754,29 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
Inokura, Fujiwara, Saito, Iino, Hatta, Okitsu, Fukuhara, Onishi, Ishizawa, Shimoda, Harigae: "Impact of TET2 deficiency on iron metabolism in erythroblasts." in: Experimental hematology, Vol. 49, pp. 56-67.e5, (2017) (PubMed).
Chou, Gatti, Fuller, Concannon, Wong, Chada, Davis, Salser: "Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro." in: Molecular and cellular biology, Vol. 6, Issue 2, pp. 566-73, (1987) (PubMed).
Boyd, Vecoli, Belcher, Jain, Drysdale: "Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones." in: The Journal of biological chemistry, Vol. 260, Issue 21, pp. 11755-61, (1985) (PubMed).
Costanzo, Santoro, Colantuoni, Bensi, Raugei, Romano, Cortese: "Cloning and sequencing of a full length cDNA coding for a human apoferritin H chain: evidence for a multigene family." in: The EMBO journal, Vol. 3, Issue 1, pp. 23-7, (1984) (PubMed).
Aliase für FTH1 Proteine
ferritin heavy chain 1 (FTH1) Proteine ferritin, heavy polypeptide 1 L homeolog (fth1.L) Proteine ferritin, heavy polypeptide 1 S homeolog (fth1.S) Proteine ferritin heavy polypeptide 1 (Fth1) Proteine ferritin heavy chain 1 (Fth1) Proteine ferritin, heavy polypeptide 1a (fth1a) Proteine ferritin (EAMY_RS19690) Proteine ferritin, heavy polypeptide 1 (fth1) Proteine tudor domain containing 9 (TDRD9) Proteine ferritin, heavy polypeptide 1 (FTH1) Proteine ferritin, heavy polypeptide 1 a (fth1a) Proteine apoferritin Proteine fb06g09 Proteine ferritin Proteine FHC Proteine fhc Proteine FTH Proteine fth Proteine Fth Proteine fth1 Proteine fth1b Proteine FTHL6 Proteine fthl6 Proteine ftn-2 Proteine HFt Proteine hm:zeh1145 Proteine MFH Proteine PIG15 Proteine pig15 Proteine PLIF Proteine plif Proteine wu:fb06g09 Proteine wu:fq18c10 Proteine zeh1145 Proteine