FTH1 Protein (AA 2-183, full length) (GST tag)

Produktnummer ABIN1095588

Produktdetails

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-183, full length

Reaktivität: Bitte anfragen

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses FTH1 Protein ist gelabelt mit GST tag.

Applikation: ELISA

Sequenz: TTASTSQVRQ NYHQDSEAAI NRQINLELYA SYVYLSMSYY FDRDDVALKN FAKYFLHQSH EEREHAEKLM KLQNQRGGRI FLQDIKKPDC DDWESGLNAM ECALHLEKNV NQSLLELHKL ATDKNDPHLC DFIETHYLNE QVKAIKELGD HVTNLRKMGA PESGLAEYLF DKHTLGDSDN ES

Produktmerkmale: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Reinheit: 90 %

Anwendungsinformationen

Kommentare:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handhabung: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Referenzen

Chou, Gatti, Fuller, Concannon, Wong, Chada, Davis, Salser: "Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro." in: Molecular and cellular biology, Vol. 6, Issue 2, pp. 566-73, (1987) (PubMed).

Boyd, Vecoli, Belcher, Jain, Drysdale: "Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones." in: The Journal of biological chemistry, Vol. 260, Issue 21, pp. 11755-61, (1985) (PubMed).

Costanzo, Santoro, Colantuoni, Bensi, Raugei, Romano, Cortese: "Cloning and sequencing of a full length cDNA coding for a human apoferritin H chain: evidence for a multigene family." in: The EMBO journal, Vol. 3, Issue 1, pp. 23-7, (1984) (PubMed).

Antigendetails

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Andere Bezeichnung: Ferritin heavy chain protein (FTH1 Produkte)

Synonyme: FHC Protein, FTH Protein, FTHL6 Protein, PIG15 Protein, PLIF Protein, apoferritin Protein, ferritin Protein, fhc Protein, fth Protein, fth1 Protein, fthl6 Protein, ftn-2 Protein, pig15 Protein, plif Protein, fth1b Protein, Fth Protein, HFt Protein, MFH Protein, fb06g09 Protein, hm:zeh1145 Protein, wu:fb06g09 Protein, wu:fq18c10 Protein, zeh1145 Protein, ferritin heavy chain 1 Protein, ferritin, heavy polypeptide 1 L homeolog Protein, ferritin, heavy polypeptide 1 S homeolog Protein, ferritin heavy polypeptide 1 Protein, ferritin, heavy polypeptide 1a Protein, ferritin Protein, ferritin, heavy polypeptide 1 Protein, tudor domain containing 9 Protein, ferritin, heavy polypeptide 1 a Protein, FTH1 Protein, fth1.L Protein, fth1.S Protein, Fth1 Protein, fth1a Protein, EAMY_RS19690 Protein, fth1 Protein, TDRD9 Protein

Hintergrund: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney

Molekulargewicht: 48.5 kD

UniProt: P25800

Pathways: Transition Metal Ion Homeostasis