The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008].
FGF19
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
FGF19
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Becker-Pauly, Barré, Schilling, Auf dem Keller, Ohler, Broder, Schütte, Kappelhoff, Stöcker, Overall: "Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 9, pp. M111.009233, (2011) (PubMed).