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neonatal Fc Receptor Proteine

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

Gesetzte Filter:

  • Target: FcRn
  • Protein
Catalog no. Produkt Reaktivität Wirt / Klonalität Anwendung Preis & Lieferzeit
ABIN7866698
FcRn Protein (AA 24-297) (His tag) FcRn · Protein Human HEK-293 Cells
789,23 € Preis anzeigen
  • 50 μg
Lieferung in 6 bis 9 Werktagen Lieferung nach: Deutschland
ABIN7950699
FcRn Protein (His tag) FcRn · Protein Maus Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Angegebene Anwendung)
  • WB (Western Blotting: Angegebene Anwendung)
  • Imm (Immunogen: Angegebene Anwendung)
  • ELISA (ELISA: Angegebene Anwendung)
503,00 € Preis anzeigen
  • 100 μg
  • 1 mg
  • 50 μg
Lieferung in 12 bis 17 Werktagen Lieferung nach: Deutschland
ABIN7943515
FcRn Protein (His tag) FcRn · Protein Human Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Angegebene Anwendung)
  • WB (Western Blotting: Angegebene Anwendung)
  • Imm (Immunogen: Angegebene Anwendung)
  • ELISA (ELISA: Angegebene Anwendung)
503,00 € Preis anzeigen
  • 100 μg
  • 1 mg
  • 50 μg
Lieferung in 12 bis 17 Werktagen Lieferung nach: Deutschland
ABIN2720991
FcRn Protein (Transcript Variant 2) FcRn · Protein Human HEK-293 Cells
  • AbP (Antibody Production: Angegebene Anwendung)
  • STD (Standard: Angegebene Anwendung)
394,23 € Preis anzeigen
  • 10 μg
Lieferung in 8 bis 14 Werktagen Lieferung nach: Deutschland
Protein
Spezies
Human
Wirt
HEK-293 Cells
Protein-Typ
Recombinant
Reinheit
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7866698
789,23 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen
Protein
  • SDS (SDS-PAGE: Angegebene Anwendung)
  • WB (Western Blotting: Angegebene Anwendung)
  • Imm (Immunogen: Angegebene Anwendung)
  • ELISA (ELISA: Angegebene Anwendung)
Spezies
Maus
Wirt
Escherichia coli (E. coli)
Protein-Typ
Recombinant
Produktnummer ABIN7950699
503,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg (Weitere Mengeneinheiten)
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
Protein
  • SDS (SDS-PAGE: Angegebene Anwendung)
  • WB (Western Blotting: Angegebene Anwendung)
  • Imm (Immunogen: Angegebene Anwendung)
  • ELISA (ELISA: Angegebene Anwendung)
Spezies
Human
Wirt
Escherichia coli (E. coli)
Protein-Typ
Recombinant
Produktnummer ABIN7943515
503,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg (Weitere Mengeneinheiten)
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
Protein
  • AbP (Antibody Production: Angegebene Anwendung)
  • STD (Standard: Angegebene Anwendung)
Spezies
Human
Wirt
HEK-293 Cells
Protein-Typ
Recombinant
Reinheit
> 95 % as determined by SDS-PAGE and Coomassie blue staining
Produktnummer ABIN2720991
394,23 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach: Deutschland
Lieferung in 8 bis 14 Werktagen

Aktuelle Publikationen für unsere neonatal Fc Receptor Proteine

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." in: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." in: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." in: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." in: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." in: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." in: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." in: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Aliase für neonatal Fc Receptor Proteine

Fc fragment of IgG receptor and transporter (FCGRT) Proteine
Fc fragment of IgG receptor and transporter (Fcgrt) Proteine
Fc receptor, IgG, alpha chain transporter (Fcgrt) Proteine
alpha-chain Proteine
FCRN Proteine
FcRn Proteine
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