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F13A1 Proteine

(Coagulation Factor XIII, A1 Polypeptide (F13A1))
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits\; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008].

11 Treffer

F13A1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Produktnummer ABIN1353305
 
F13A1 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319648
 
F13A1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7576884
 
F13A1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, PC, Imm
Produktnummer ABIN7393214
 
F13A1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, PC, Imm
Produktnummer ABIN7415719
 
F13A1 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant >95 % WB, SDS, PC, Imm
Produktnummer ABIN7411717
 
F13A1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2712929
 
F13A1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, PC
Produktnummer ABIN2749986
 
F13A1 Spezies: Human Wirt: Human Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE. WB, SDS, ELISA, MS
Produktnummer ABIN7314318
 
F13A1 Spezies: Rind (Kuh) Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7584270
 
F13A1 Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7584271
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Positive Control (PC)
    • Immunogen (Imm)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Mass Spectrometry (MS)
    • Standard (STD)
  • Reaktivität
    • Human
    • Rat
    • Cow
    • Mouse
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • Human Cells
    • Yeast
    • HEK-293 Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 39-732
    • AA 1-732
    • AA 107-345
    • AA 140-377
    • AA 372-616
    • AA 39-198
  • Konjugat
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
    • Frozen
  • Hersteller
    • antibodies-online
    • CUSABIO
    • Cohesion Biosciences
    • FabGennix
    • OriGene

Aliase für F13A1 Proteine

coagulation factor XIII A1 chain (F13a1) Proteine
coagulation factor XIII, A1 polypeptide b (f13a1b) Proteine
coagulation factor XIII A chain (F13A1) Proteine
coagulation factor XIII, A1 subunit (F13a1) Proteine
coagulation factor XIII A chain (F13a1) Proteine
1200014I03Rik Proteine
AI462306 Proteine
F13a Proteine
F13A Proteine
f13a1 Proteine
F13A1 Proteine
wu:fo83d04 Proteine
zgc:153334 Proteine
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