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F13A1 Produkte

(Coagulation Factor XIII, A1 Polypeptide (F13A1))

Kategorien

This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits\; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008].

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Ausgewählte F13A1 Kategorien

F13A1 Antikörper

High quality antibodies with extensive validation data.

F13A1 ELISA Kits

Reliable ELISA kits for a wide range of species.

F13A1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene F13A1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation FACS, IF, IHC, IHC (p), WB
Validierungen
  • (8)
Kat. Nr. ABIN1498146
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, IHC (p), WB
Validierungen
  • (10)
Kat. Nr. ABIN1498149
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, IHC (p), WB
Validierungen
  • (11)
Kat. Nr. ABIN1498150
Menge 100 μL
Datenblatt Datenblatt

Empfohlene F13A1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965912
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962106
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954886
Menge 96 tests
Datenblatt Datenblatt

Empfohlene F13A1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3079512
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3124778
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1353305
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren F13A1 Produkten

Wang, Yang, Ran: "Localized papular mucinosis with IgA nephropathy: a case report." in: Archives of dermatology, Vol. 147, Issue 5, pp. 599-602, (2011) (PubMed).

Higaki, Nakano, Onaka, Amano, Tanioka, Harada, Hashimoto, Sakaida, Okita: "Clinical significance of measuring blood coagulation factor XIIIA regularly and continuously in patients with Crohn's disease." in: Journal of gastroenterology and hepatology, Vol. 21, Issue 9, pp. 1407-11, (2006) (PubMed).

Davie, Fujikawa, Kisiel: "The coagulation cascade: initiation, maintenance, and regulation." in: Biochemistry, Vol. 30, Issue 43, pp. 10363-70, (1991) (PubMed).

Synonyme und alternative Namen zu F13A1

coagulation factor XIII A1 chain (F13a1), coagulation factor XIII, A1 polypeptide b (f13a1b), coagulation factor XIII A chain (F13A1), coagulation factor XIII, A1 subunit (F13a1), coagulation factor XIII A chain (F13a1), 1200014I03Rik, AI462306, F13a, F13A, f13a1, F13A1, wu:fo83d04, zgc:153334

Bezeichner auf Proteinebene für F13A1

  • coagulation factor XIII A chain
  • coagulation factor XIII, A1 subunit
  • coagulation factor XIIIa
  • protein-glutamine gamma-glutamyltransferase A chain
  • transglutaminase A chain
  • FX111a-87
  • fo83d04
  • coagulation factor XIII A1 subunit
  • coagulation factor XIII, A1 polypeptide
  • blood coagulation factor XIII A1 subunit
  • coagulation factor XIIIA
  • Coagulation factor XIII A chain
  • FSF, A subunit
  • TGase
  • bA525O21.1 (coagulation factor XIII, A1 polypeptide)
  • coagulation factor XIII, A polypeptide
  • factor XIIIa
  • fibrin stabilizing factor, A subunit
  • fibrinoligase
  • transglutaminase. plasma
  • Factor XIIIA
  • coagulation factor XIII, alpha subunit
  • coagulation factor XIII A chain-like
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