F13A1 Produkte
(Coagulation Factor XIII, A1 Polypeptide (F13A1))
Kategorien
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits\; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008].
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Ausgewählte F13A1 Kategorien
F13A1 Antikörper
High quality antibodies with extensive validation data.
F13A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
F13A1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene F13A1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7433159
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (10)
Kat. Nr.
ABIN7442897
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7440509
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene F13A1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965912
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962106
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954886
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene F13A1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353305
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Human Cells
Validierungen
Kat. Nr.
ABIN7319648
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7576884
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren F13A1 Produkten
: "Localized papular mucinosis with IgA nephropathy: a case report." in: Archives of dermatology, Vol. 147, Issue 5, pp. 599-602, (2011) (PubMed).: "Clinical significance of measuring blood coagulation factor XIIIA regularly and continuously in patients with Crohn's disease." in: Journal of gastroenterology and hepatology, Vol. 21, Issue 9, pp. 1407-11, (2006) (PubMed).
: "The coagulation cascade: initiation, maintenance, and regulation." in: Biochemistry, Vol. 30, Issue 43, pp. 10363-70, (1991) (PubMed).
Synonyme und alternative Namen zu F13A1
coagulation factor XIII A1 chain (F13a1), coagulation factor XIII, A1 polypeptide b (f13a1b), coagulation factor XIII A chain (F13A1), coagulation factor XIII, A1 subunit (F13a1), coagulation factor XIII A chain (F13a1), 1200014I03Rik, AI462306, F13a, F13A, f13a1, F13A1, wu:fo83d04, zgc:153334Bezeichner auf Proteinebene für F13A1
- coagulation factor XIII A chain
- coagulation factor XIII, A1 subunit
- coagulation factor XIIIa
- protein-glutamine gamma-glutamyltransferase A chain
- transglutaminase A chain
- FX111a-87
- fo83d04
- coagulation factor XIII A1 subunit
- coagulation factor XIII, A1 polypeptide
- blood coagulation factor XIII A1 subunit
- coagulation factor XIIIA
- Coagulation factor XIII A chain
- FSF, A subunit
- TGase
- bA525O21.1 (coagulation factor XIII, A1 polypeptide)
- coagulation factor XIII, A polypeptide
- factor XIIIa
- fibrin stabilizing factor, A subunit
- fibrinoligase
- transglutaminase. plasma
- Factor XIIIA
- coagulation factor XIII, alpha subunit
- coagulation factor XIII A chain-like
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