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FAS Produkte

(TNF Receptor Superfamily, Member 6 (FAS))

Kategorien

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011].

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Ausgewählte FAS Kategorien

FAS Antikörper

High quality antibodies with extensive validation data.

FAS ELISA Kits

Reliable ELISA kits for a wide range of species.

FAS Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FAS Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ICC, FACS, ELISA, WB
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN969518
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Mouse, Rat
Applikation IHC (fro), IHC (p), WB
Validierungen
  • (19)
  • (4)
Kat. Nr. ABIN3044338
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation IF, ELISA, WB
Validierungen
  • (5)
Kat. Nr. ABIN3030902
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene FAS ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (3)
  • (6)
Kat. Nr. ABIN6730941
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN6955699
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6955700
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FAS Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7274589
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7274590
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7274587
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FAS Produkten

Malik, Pal, Gupta: "EGF-mediated reduced miR-92a-1-5p controls HTR-8/SVneo cell invasion through activation of MAPK8 and FAS which in turn increase MMP-2/-9 expression." in: Scientific reports, Vol. 10, Issue 1, pp. 12274, (2020) (PubMed).

Yang, Wang, Sun, Zhang, Guo, Shi, Cheng, Tang, Le: "Dietary methionine restriction reduces hepatic steatosis and oxidative stress in high-fat-fed mice by promoting H2S production." in: Food & function, Vol. 10, Issue 1, pp. 61-77, (2019) (PubMed).

Teng, Wu, Lin, Wu, Wang, Chen, Chen: "Danshensu Decreases UVB-Induced Corneal Inflammation in an Experimental Mouse Model via Oral Administration." in: Current eye research, Vol. 43, Issue 1, pp. 27-34, (2018) (PubMed).

Garcia-Obregon, Azkargorta, Seijas, Pilar-Orive, Borrego, Elortza, Boyano, Astigarraga: "Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients." in: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, Vol. 51, Issue 4, pp. 465-472, (2018) (PubMed).

Qian, Zhang, Zhou, Liu, Yue, Guo, Sun, Lv, Chen: "Artesunate enhances γδ T-cell-mediated antitumor activity through augmenting γδ T-cell function and reversing immune escape of HepG2 cells." in: Immunopharmacology and immunotoxicology, Vol. 40, Issue 2, pp. 107-116, (2018) (PubMed).

Dodi, Ajayi, Chang, Beard, Ashley, Huang, Thannickal, Tschumperlin, Sisson, Horowitz: "Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli." in: Respiratory research, Vol. 19, Issue 1, pp. 91, (2018) (PubMed).

Sprague, Troyer, Zheng, Wood, Macmillian, Carver, VandeWoude: "Prior Puma Lentivirus Infection Modifies Early Immune Responses and Attenuates Feline Immunodeficiency Virus Infection in Cats." in: Viruses, Vol. 10, Issue 4, (2018) (PubMed).

Cao, Liu, Huang, Wang, Jiao, Huo: "SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3115-3126, (2018) (PubMed).

Attia, Nounou, Shalaby: "Zinc Oxide Nanoparticles Induced Oxidative DNA Damage, Inflammation and Apoptosis in Rat's Brain after Oral Exposure." in: Toxics, Vol. 6, Issue 2, (2018) (PubMed).

Vodret, Bortolussi, Jašprová, Vitek, Muro: "Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 (-/-) mouse model." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 64, (2017) (PubMed).

Synonyme und alternative Namen zu FAS

Fas cell surface death receptor (FAS), Fas ligand (FASLG), Fas ligand (TNF superfamily, member 6) (Fasl), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ), Fas (TNF receptor superfamily member 6) (Fas), Fas cell surface death receptor (Fas), Fas cell surface death receptor (fas), AI196731, ALPS1A, APO-1, APO1, APT1, APT1LG1, CD95, CD95-L, CD95L, CD178, Fas-L, FAS1, FASL, Faslg, FASTM, gld, lpr, TNFR6, TNFRSF6, Tnfrsf6, TNFSF6, Tnfsf6

Bezeichner auf Proteinebene für FAS

  • APO-1 cell surface antigen
  • CD95 antigen
  • Delta Fas/APO-1/CD95
  • FAS 827dupA
  • FASLG receptor
  • Fas (TNF receptor superfamily, member 6)
  • Fas AMA
  • TNF receptor superfamily member 6
  • apoptosis antigen 1
  • apoptosis-mediating surface antigen FAS
  • tumor necrosis factor receptor superfamily member 6
  • tumor necrosis factor receptor superfamily, member 6
  • fas antigen ligand
  • tumor necrosis factor (ligand) superfamily, member 6
  • tumor necrosis factor ligand superfamily member 6
  • APO-1 ligand
  • CD95 ligand
  • TNF superfamily, member 6
  • Fas antigen
  • Fas antigen ligand
  • generalized lymphoproliferative disease
  • 14-3-3 protein zeta/delta
  • FAS
  • KCIP-1
  • factor activating exoenzyme S
  • protein kinase C inhibitor protein 1
  • Fas (TNF receptor superfamily member)
  • apo-1 antigen
  • lymphoproliferation
  • Fas antigen (ATP1)
  • Fas receptor
  • Tumor necrosis factor receptor superfamily, member 6
  • apoptosis (APO-1) antigen 1 ( FAS ), member 6
  • Fas receptor CD95
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