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FAM84A Proteine

(Family with Sequence Similarity 84, Member A (FAM84A))
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus.

5 Treffer

FAM84A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Produktnummer ABIN7122885
 
FAM84A Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
Produktnummer ABIN1353598
 
FAM84A Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pubmed 1 reference
Produktnummer ABIN2727638
 
FAM84A Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
Produktnummer ABIN2129181
 
FAM84A Spezies: Rind (Kuh) Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7589541
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • SDS-PAGE (SDS)
    • Standard (STD)
  • Reaktivität
    • Human
    • Cow
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • Bindungsspezifität
    • AA 1-292
    • AA 1-297
  • Konjugat
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • Unkonjugiert
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Hersteller
    • antibodies-online
    • CUSABIO
    • OriGene

Aktuelle Publikationen für unsere FAM84A Proteine

Brändle, Obermeier, Senel, Bruder, Mentele, Khademi, Olsson, Tumani, Kristoferitsch, Lottspeich, Wekerle, Hohlfeld, Dornmair: "Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 28, pp. 7864-9, (2016) (PubMed).

Aliase für FAM84A Proteine

family with sequence similarity 84, member A (Fam84a) Proteine
family with sequence similarity 84 member A (FAM84A) Proteine
family with sequence similarity 84, member A (fam84a) Proteine
family with sequence similarity 84 member A (Fam84a) Proteine
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