ErbB2/Her2 Proteine
(Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008].
Ergebnisse filtern:
99 Treffer
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
KAA
Active
Produktnummer ABIN7856279
-20% for 20 Years of ABO
349,05 €
Sparen Sie 87,26 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
KAA
Active
Produktnummer ABIN7856282
-20% for 20 Years of ABO
340,43 €
Sparen Sie 85,11 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
KAA
Active
Produktnummer ABIN7856281
-20% for 20 Years of ABO
340,43 €
Sparen Sie 85,11 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
KAA
Active
Produktnummer ABIN7856284
-20% for 20 Years of ABO
340,43 €
Sparen Sie 85,11 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
KAA
Produktnummer ABIN7856278
-20% for 20 Years of ABO
340,43 €
Sparen Sie 85,11 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
KAA
Produktnummer ABIN7856280
-20% for 20 Years of ABO
340,43 €
Sparen Sie 85,11 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
KAA
Active
Produktnummer ABIN7856283
-20% for 20 Years of ABO
340,43 €
Sparen Sie 85,11 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
KAA
Active
Produktnummer ABIN7856277
-20% for 20 Years of ABO
340,43 €
Sparen Sie 85,11 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
Active
Produktnummer ABIN7856287
-20% for 20 Years of ABO
349,05 €
Sparen Sie 87,26 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
KAA
Active
Produktnummer ABIN7856271
-20% for 20 Years of ABO
349,05 €
Sparen Sie 87,26 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
Active
Produktnummer ABIN7856288
-20% for 20 Years of ABO
349,05 €
Sparen Sie 87,26 € (-20 %)
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
10 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 12 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % , as determined by SDS-PAGE and HPLC
Produktnummer ABIN7865938
-20% for 20 Years of ABO
773,38 €
Sparen Sie 193,35 € (-20 %)
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
Lieferung nach:
Deutschland
Lieferung in 6 bis 7 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Produktnummer ABIN7890164
-20% for 20 Years of ABO
1.579,22 €
Sparen Sie 394,81 € (-20 %)
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach:
Deutschland
Lieferung in 8 bis 10 Werktagen
ErbB2/Her2
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 97 % by SDS-PAGE.
Active
Produktnummer ABIN7534934
-20% for 20 Years of ABO
272,00 €
Sparen Sie 68,00 € (-20 %)
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 7 bis 9 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % , as determined by SDS-PAGE and HPLC
Produktnummer ABIN7865937
-20% for 20 Years of ABO
773,38 €
Sparen Sie 193,35 € (-20 %)
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
Lieferung nach:
Deutschland
Lieferung in 6 bis 7 Werktagen
ErbB2/Her2
Spezies: Ratte
Wirt: Mammalian Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
Produktnummer ABIN7665224
-20% for 20 Years of ABO
492,30 €
Sparen Sie 123,08 € (-20 %)
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 13 bis 18 Werktagen
ErbB2/Her2
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
ScA, AM, ADA, IA
Produktnummer ABIN7853134
-20% for 20 Years of ABO
697,85 €
Sparen Sie 174,46 € (-20 %)
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 10 bis 13 Werktagen
Produktnummer ABIN7385953
-20% for 20 Years of ABO
7.666,36 €
Sparen Sie 1.916,59 € (-20 %)
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach:
Deutschland
Lieferung in 7 bis 10 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: Human Cells
Recombinant
Produktnummer ABIN7890165
-20% for 20 Years of ABO
790,37 €
Sparen Sie 197,59 € (-20 %)
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 8 bis 10 Werktagen
ErbB2/Her2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
ELISA
Active
Produktnummer ABIN7197648
-20% for 20 Years of ABO
596,80 €
Sparen Sie 149,20 € (-20 %)
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 9 bis 13 Werktagen
Aktuelle Publikationen für unsere ErbB2/Her2 Proteine
: "Heavy chain dimers stabilized by disulfide bonds are required to promote in vitro assembly of trastuzumab." in: BMC molecular and cell biology, Vol. 21, Issue 1, pp. 2, (2020) (PubMed).
: "Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system." in: Scientific reports, Vol. 9, Issue 1, pp. 671, (2020) (PubMed).
: "Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex." in: PLoS ONE, Vol. 14, Issue 5, pp. e0216095, (2020) (PubMed).
: "Dual-Affinity Ratiometric Quenching (DARQ) Assay for the Quantification of Therapeutic Antibodies in CHO-S Cell Culture Fluids." in: Analytical chemistry, Vol. 92, Issue 24, pp. 16274-16283, (2020) (PubMed).
: "Assessing Analytical and Functional Similarity of Proposed Amgen Biosimilar ABP 980 to Trastuzumab." in: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, Vol. 33, Issue 3, pp. 321-333, (2019) (PubMed).
: "Isolation and characterization of camelid single-domain antibodies against HER2." in: BMC research notes, Vol. 11, Issue 1, pp. 866, (2019) (PubMed).
: "Efficient generation of single domain antibodies with high affinities and enhanced thermal stabilities." in: Scientific reports, Vol. 7, Issue 1, pp. 5794, (2019) (PubMed).
: "Anti-HER2 scFv-Directed Extracellular Vesicle-Mediated mRNA-Based Gene Delivery Inhibits Growth of HER2-Positive Human Breast Tumor Xenografts by Prodrug Activation." in: Molecular cancer therapeutics, Vol. 17, Issue 5, pp. 1133-1142, (2019) (PubMed).
: "Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins." in: Bioconjugate chemistry, Vol. 29, Issue 9, pp. 3016-3025, (2019) (PubMed).
: "The Impact of FcγRI Binding on ImmunoPET." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, (2019) (PubMed).
: "Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system." in: Scientific reports, Vol. 9, Issue 1, pp. 671, (2020) (PubMed).
: "Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex." in: PLoS ONE, Vol. 14, Issue 5, pp. e0216095, (2020) (PubMed).
: "Dual-Affinity Ratiometric Quenching (DARQ) Assay for the Quantification of Therapeutic Antibodies in CHO-S Cell Culture Fluids." in: Analytical chemistry, Vol. 92, Issue 24, pp. 16274-16283, (2020) (PubMed).
: "Assessing Analytical and Functional Similarity of Proposed Amgen Biosimilar ABP 980 to Trastuzumab." in: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, Vol. 33, Issue 3, pp. 321-333, (2019) (PubMed).
: "Isolation and characterization of camelid single-domain antibodies against HER2." in: BMC research notes, Vol. 11, Issue 1, pp. 866, (2019) (PubMed).
: "Efficient generation of single domain antibodies with high affinities and enhanced thermal stabilities." in: Scientific reports, Vol. 7, Issue 1, pp. 5794, (2019) (PubMed).
: "Anti-HER2 scFv-Directed Extracellular Vesicle-Mediated mRNA-Based Gene Delivery Inhibits Growth of HER2-Positive Human Breast Tumor Xenografts by Prodrug Activation." in: Molecular cancer therapeutics, Vol. 17, Issue 5, pp. 1133-1142, (2019) (PubMed).
: "Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins." in: Bioconjugate chemistry, Vol. 29, Issue 9, pp. 3016-3025, (2019) (PubMed).
: "The Impact of FcγRI Binding on ImmunoPET." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, (2019) (PubMed).
Aliase für ErbB2/Her2 Proteine
erb-b2 receptor tyrosine kinase 2 (ERBB2) Proteineerb-b2 receptor tyrosine kinase 2 (Erbb2) Proteine
erb-b2 receptor tyrosine kinase 2 (erbb2) Proteine
c-erbB2 Proteine
c-neu Proteine
CD340 Proteine
erb2 Proteine
Erbb-2 Proteine
HER-2 Proteine
HER-2/neu Proteine
HER2 Proteine
mKIAA3023 Proteine
MLN 19 Proteine
NEU Proteine
Neu Proteine
NGL Proteine
TKR1 Proteine
wu:fv70f10 Proteine
zgc:63601 Proteine
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