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Recommendations are based on data provided indicating:
  • ELISA Kit Sensitivity
    The recommended ELISA Kit will likely detect the antigen better in the approved sample types than the available alternatives.
  • ELISA Kit Specificity
    The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
  • Experiment Reproducibility
    The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
  • ELISA Kit Robustness
    The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
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PTK2B Antigen Profile

Beschreibung des Gens

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • protein tyrosine kinase 2 beta (PTK2B) ELISA Kit
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) ELISA Kit
  • protein tyrosine kinase 2 beta (Ptk2b) ELISA Kit
  • protein tyrosine kinase 2aa (ptk2aa) ELISA Kit
  • FAK2 ELISA Kit
  • PYK2 ELISA Kit
  • CAKbeta ELISA Kit
  • E430023O05Rik ELISA Kit
  • Raftk ELISA Kit
  • Pyk2 ELISA Kit
  • fak1b ELISA Kit
  • ptk2.2 ELISA Kit
  • ptk2b ELISA Kit
  • si:ch1073-355e8.1 ELISA Kit

Bezeichner auf Proteinebene für PTK2B

CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , cellular adhesion kinase beta , protein tyrosine kinase 2 beta , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , fakb , protein tyrosine kinase 2.2 , protein tyrosine kinase 2aa , protein tyrosine kinase 2b

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