Dynactin 1 Produkte
(Dynactin 1 (DCTN1))
Kategorien
This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq, Oct 2008].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte Dynactin 1 Kategorien
Dynactin 1 Antikörper
High quality antibodies with extensive validation data.
Dynactin 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Dynactin 1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Dynactin 1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF, FACS
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN184834
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, ICC, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN2854663
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Chicken, Dog, Human, Mouse, Rat
Applikation
WB, IF, IP, IHC (zinc)
Validierungen
- (5)
- (4)
Kat. Nr.
ABIN967996
Menge
150 μg
Datenblatt
Datenblatt
Empfohlene Dynactin 1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4882617
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Dynactin 1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7553616
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7562204
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351220
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Dynactin 1 Produkten
: "The hnRNP raly regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization." in: Molecular biology of the cell, pp. mbcE18020108, (2018) (PubMed).: "Temporal changes in expression of connexin 43 after load-induced hypertrophy in vitro." in: American journal of physiology. Heart and circulatory physiology, Vol. 296, Issue 3, pp. H806-14, (2009) (PubMed).
: "Anthrax toxin rafts into cells." in: The Journal of cell biology, Vol. 160, Issue 3, pp. 295-6, (2003) (PubMed).
: "Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome." in: Molecular biology of the cell, Vol. 13, Issue 10, pp. 3627-45, (2002) (PubMed).
: "NudC associates with Lis1 and the dynein motor at the leading pole of neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 24, pp. RC187, (2001) (PubMed).
: "Cytoplasmic dynein regulation by subunit heterogeneity and its role in apical transport." in: The Journal of cell biology, Vol. 153, Issue 7, pp. 1499-509, (2001) (PubMed).
: "Dynactin increases the processivity of the cytoplasmic dynein motor." in: Nature cell biology, Vol. 2, Issue 1, pp. 20-4, (2000) (PubMed).
: "Localization of the DCTN1 gene encoding p150Glued to human chromosome 2p13 by fluorescence in situ hybridization." in: Genomics, Vol. 31, Issue 3, pp. 398-9, (1997) (PubMed).
: "The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1634-8, (1995) (PubMed).
: "Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued." in: Nature, Vol. 351, Issue 6327, pp. 579-83, (1991) (PubMed).
Synonyme und alternative Namen zu Dynactin 1
dynactin subunit 1 (DCTN1), dynactin subunit 1 (Dctn1), dynactin 1 (Dctn1), Dynactin 1, p150 subunit (DCTN1-p150), dynactin subunit 1 L homeolog (dctn1.L), AL022633, CG9206, Chip150, DAP-150, DCTN1, DKFZp469C1813, Dmel\\CG9206, DP-150, Dynactin-1, DYNA_DROME, FCP-D, Glu, Glued, glued, P135, p150, P150, p150/Glued, p150/glued, p150Bezeichner auf Proteinebene für Dynactin 1
- 150 kDa dynein-associated polypeptide
- dynactin 1 (p150, glued homolog, Drosophila)
- dynactin subunit 1
- DAP-150
- DP-150
- p150-glued
- dynactin 1
- dynactin subunit 1-like
- dynactin 1, retrograde axonal transport
- CG9206-PA
- Gl-PA
- dynactin
- dynactin P150
- glued
- p150[glued]
- p150glued
- dynactin 1 (p150, glued homolog)
Sie sind hier:
