DUOXA1 Produkte
(Dual Oxidase Maturation Factor 1 (DUOXA1))
Kategorien
Dual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2, respectively, which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg), a macromolecular precursor in thyroid hormone synthesis, while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013].
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Ausgewählte DUOXA1 Kategorien
DUOXA1 Antikörper
High quality antibodies with extensive validation data.
DUOXA1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DUOXA1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN530004
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF
Validierungen
- (1)
Kat. Nr.
ABIN7150692
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Pig
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN6747594
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene DUOXA1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352082
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352084
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3078973
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DUOXA1 Produkten
: "DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties." in: Oncogenesis, Vol. 5, Issue 10, pp. e261, (2016) (PubMed).: "Dual oxidase maturation factor 1 (DUOXA1) overexpression increases reactive oxygen species production and inhibits murine muscle satellite cell differentiation." in: Cell communication and signaling : CCS, Vol. 12, pp. 5, (2014) (PubMed).
: "NIP1/DUOXA1 expression in epithelial breast cancer cells: regulation of cell adhesion and actin dynamics." in: Breast cancer research and treatment, Vol. 119, Issue 3, pp. 773-86, (2010) (PubMed).
Synonyme und alternative Namen zu DUOXA1
dual oxidase maturation factor 2 (DUOXA2), dual oxidase maturation factor 1 (DUOXA1), dual oxidase maturation factor 1 (LOC100405759), dual oxidase maturation factor 1 (Duoxa1), BC019755, mol, NIP, Nip, Nip1, NUMBIP, RGD1306601Bezeichner auf Proteinebene für DUOXA1
- dual oxidase maturation factor 1
- Numb-interacting protein
- dual oxidase activator 1
- dual oxidase maturation factor 1 alpha
- dual oxidase maturation factor 1 beta
- dual oxidase maturation factor 1 delta
- dual oxidase maturation factor 1 gamma
- homolog of Drosophila Numb-interacting protein
- Numb-interacting protein 1
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