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DRAP1 Proteine

(DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008].

5 Treffer :

DRAP1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, AA, AP, WB
Produktnummer ABIN1352006
 
DRAP1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
Pubmed 5 Referenzen
Produktnummer ABIN1046948
 
DRAP1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2719758
 
DRAP1 Spezies: Rind (Kuh) Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7588632
 
DRAP1 Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7584163
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
    • Western Blotting (WB)
  • Reaktivität
    • Human
    • Cow
    • Rat
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Yeast
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 2-205
    • AA 1-205
    • AA 4-198
    • partial
  • Konjugat
    • GST tag
    • His tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
  • Hersteller
    • CUSABIO
    • OriGene
    • antibodies-online

Aktuelle Publikationen für unsere DRAP1 Proteine

Burkard, Planyavsky, Kaupe, Breitwieser, Bürckstümmer, Bennett, Superti-Furga, Colinge: "Initial characterization of the human central proteome." in: BMC systems biology, Vol. 5, pp. 17, (2011) (PubMed).

Klejman, Pereira, van Zeeburg, Gilfillan, Meisterernst, Timmers: "NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 10072-82, (2004) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Goppelt, Stelzer, Lottspeich, Meisterernst: "A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains." in: The EMBO journal, Vol. 15, Issue 12, pp. 3105-16, (1996) (PubMed).

Mermelstein, Yeung, Cao, Inostroza, Erdjument-Bromage, Eagelson, Landsman, Levitt, Tempst, Reinberg: "Requirement of a corepressor for Dr1-mediated repression of transcription." in: Genes & development, Vol. 10, Issue 8, pp. 1033-48, (1996) (PubMed).

Aliase für DRAP1 Proteine

DR1-associated protein 1 (negative cofactor 2 alpha) (drap1) Proteine
DR1 associated protein 1 (DRAP1) Proteine
Dr1 associated protein 1 (negative cofactor 2 alpha) (Drap1) Proteine
Dr1 associated protein 1 (Drap1) Proteine
2310074H19Rik Proteine
DRAP1 Proteine
fb26e10 Proteine
NC2-alpha Proteine
wu:fb26e10 Proteine
zgc:56003 Proteine
zgc:77337 Proteine
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