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anti-Minichromosome Maintenance Complex Component 7 (MCM7) Antikörper

Bezeichnung:: anti-Minichromosome Maintenance Complex Component 7 Antikörper (MCM7)

Auf www.antikoerper-online.de finden Sie aktuell 296 Minichromosome Maintenance Complex Component 7 (MCM7) Antikörper von 27 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Minichromosome Maintenance Complex Component 7 Proteine (6) und Minichromosome Maintenance Complex Component 7 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 314 Minichromosome Maintenance Complex Component 7 Produkte verfügbar.

Synonyme:: AI747533, anon-EST:Liang-1.66, cdc47, cdc47-2, CG4978, chunp6911, clone 1.66, Dmel\\CG4978, DmeMCM7, DmMCM7, mCDC47, MCM2, McM7, Mcmd7, Mcp-PCR1, nyz175, P1.1-MCM3, P1CDC47, P85MCM, PCR1, PNAS146, sr:nyz175, xmcm7

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	MCM7	4176	P33993
	MCM7	288532
	MCM7	17220	Q61881
Alle Spezies anzeigen Weitere Synonyme anzeigen

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Am meisten referenzierte anti-Minichromosome Maintenance Complex Component 7 Antikörper

Human Monoclonal MCM7 Primary Antibody für IF, IHC (p) - ABIN561764 : Köhler, Kreuter, Rozynkowski, Rahmel, Uhl, Tannapfel, Schmidt, Meier: Validation of different replication markers for the detection of beta-cell proliferation in human pancreatic tissue. in Regulatory peptides 2010 (PubMed)
Show all 4 Pubmed References
Human Polyclonal MCM7 Primary Antibody für ChIP, ICC - ABIN441356 : Hubbi, Luo, Baek, Semenza: MCM proteins are negative regulators of hypoxia-inducible factor 1. in Molecular cell 2011 (PubMed)
Show all 3 Pubmed References
Human Polyclonal MCM7 Primary Antibody für PLA, WB - ABIN151719 : Nash, Chen, Muzyczka: Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins. in Journal of virology 2008 (PubMed)
Show all 2 Pubmed References
Human Polyclonal MCM7 Primary Antibody für IF, IP - ABIN2452047 : Fujita, Kiyono, Hayashi, Ishibashi: hCDC47, a human member of the MCM family. Dissociation of the nucleus-bound form during S phase. in The Journal of biological chemistry 1996 (PubMed)
Show all 3 Pubmed References
Human Monoclonal MCM7 Primary Antibody für FACS, IF - ABIN5583309 : Koonin: A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication. in Nucleic acids research 1993 (PubMed)

Weitere Antikörper gegen Minichromosome Maintenance Complex Component 7 Interaktionspartner

Human Minichromosome Maintenance Complex Component 7 (MCM7) Interaktionspartner

In this study, we demonstrated for the first time that MCM2 among MCM2-7 except for MCM5 is specifically degraded, and that MCM2 and MCM7 are localized in the cytoplasm in senescent cells. To examine the relationship between the cytoplasmic localization of MCM proteins and cell cycle phase, the distribution of DNA content of cells showing cytoplasmic localization of MCM2 and MCM7 was examined.
Our study confirms that MCM7 is a valuable marker for assessing the progression of pancreatic neuroendocrine tumors, especially in patients with early stage disease and without distant metastasis.
Depletion of a second MCM (MCM7), which functions in complex with MCM2 during its canonical functions, reveals an overlapping cilia-deficiency phenotype likely unconnected to replication, although MCM7 appears to regulate a distinct subset of genes and pathways. Our data suggests that MCM2 and 7 exert a role in ciliogenesis in post-mitotic tissues.
Here, the authors show that, in human cells, cohesin loading onto chromosomes during early S phase requires the replicative helicase MCM2-7 and the kinase DDK. Cohesin and its loader SCC2/4 (NIPBL/MAU2 in humans) associate with DDK and phosphorylated MCM2-7.
Ki-67, MCM-3, and MCM-7, but not MCM-5 are reliable proliferative and diagnostic markers in discerning benign and malignant adrenocortical tumors.
Our results indicate that MCM7 may exert certain functions on spindle formation to prevent cytokinesis during early mitosis by regulating CDK1 activity.
MCM7 is helpful for us to make differential diagnosis in pathological grade, MCM7 combination of Ki67 may serve as more sensitive proliferation markers for evaluation of gastric carcinoma and precancerous lesions
CDT1, MCM7, and NUDT1 were shown to be up-regulated in hepatocellular carcinoma tissues and provide a more accurate diagnosis than alpha-fetal protein alone.
High expression of MCM-7 was reduced in BVP-treated cancer cells.
Data indicate that RACK1 increases interactions between Akt and MCM7 and promotes Akt-dependent MCM7 phosphorylation, which in turn increases MCM7 binding to chromatin and miniature chromosome maintenance (MCM) complex formation.
our findings suggested that MCM7 promoted tumor cell proliferation, colony formation and migration of ESCC cells via activating AKT1/mTOR signaling pathway
Results proved that MCM7 proliferative index is a better method for identifying patients with risk of recurrence in patients surgically resected for meningiomas compared with the traditional methods used in the current clinical practice.
MCM7-cyclin D1 pathway may participate in cancer progression.
The MCM7 directly binds to the centrosomal linker protein Cep68 in vitro and complexes with Cep68 and VHL in vivo.
The results clearly demonstrate 7q21-22 amplification, MCM7, and its intronic miR-25 are the major molecular switches involved in the complex oncogenic circuits of gastric cancer.
High MCM7 expression is associated with non-small cell lung cancer.
MCM4 and MCM7 expression is significantly correlated with Ki-67, Bmi1, and cyclin E expression in esophageal adenocarcinoma, squamous cell carcinoma and precancerous lesions.
Data suggest that interaction of Mcm10 with Mcm2-7 multimer requires Mcm10 domain that contains amino acids 530-655, which overlaps with domain required for stable retention of Mcm10 on chromatin; Mcm10 conserved domain (amino acids 200-482) is essential for DNA replication; both conserved domain and Mcm2-7-binding domain are required for full activity of Mcm10.
Results show that the expression of MCM7 gene and its microRNA, miR-106b-25 cluster is reduced under hypoxia.
This MCM4 mutation affected human MCM4/6/7 complex formation, since the complex containing the mutant MCM4 protein is unstable and the mutant MCM4 protein is tend to be degraded.

Mouse (Murine) Minichromosome Maintenance Complex Component 7 (MCM7) Interaktionspartner

Unique pattern of ORC2 and MCM7 localization during DNA replication licensing in the mouse zygote.
role of subunits in DNA helicases activity
cyclin D1/CDK4 complexes play a direct role in altering an inhibitory RB.MCM7 complex possibly allowing for setting of the origin in preparation for DNA replication
MCM7 may be a highly informative biomarker for cervical cancer.
Substrate preference and helicase actions of mouse MCM4/6/7 helicase complexes.
Accumulation and dynamics of Mcm7 are described during oogenesis and the first embryonic cell cycle.
cellular DNA replication factor MCM7 is involved in prostate cancer (CaP) and MCM7 gene expression was reduced by green tea catechins
DNA binding and helicase activities of Mcm4/6/7 are significantly stimulated by Cdt1

Xenopus laevis Minichromosome Maintenance Complex Component 7 (MCM7) Interaktionspartner

Mcm2-7 associate with Cdc45 and GINS to form a relatively stable CMG (Cdc45-MCM-GINS) complex.

Minichromosome Maintenance Complex Component 7 (MCM7) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with Minichromosome Maintenance Complex Component 7 (MCM7)

minichromosome maintenance complex component 7 (MCM7) Antikörper
mini-chromosome maintenance complex protein 7 (MCM7) Antikörper
mini-chromosome maintenance complex protein 7 (CDC47) Antikörper
minichromosome maintenance complex component 7 (Mcm7) Antikörper
minichromosome maintenance complex component 2 (MCM2) Antikörper
minichromosome maintenance complex component 7 (mcm7) Antikörper
minichromosome maintenance complex component 7 L homeolog (mcm7.L) Antikörper
Minichromosome maintenance 7 (Mcm7) Antikörper
minichromosome maintenance complex component 7 S homeolog (mcm7.S) Antikörper
MCM complex subunit Mcm7 (mcm7) Antikörper

AI747533 Antikörper
anon-EST:Liang-1.66 Antikörper
cdc47 Antikörper
cdc47-2 Antikörper
CG4978 Antikörper
chunp6911 Antikörper
clone 1.66 Antikörper
Dmel\\CG4978 Antikörper
DmeMCM7 Antikörper
DmMCM7 Antikörper
mCDC47 Antikörper
MCM2 Antikörper
McM7 Antikörper
Mcmd7 Antikörper
Mcp-PCR1 Antikörper
nyz175 Antikörper
P1.1-MCM3 Antikörper
P1CDC47 Antikörper
P85MCM Antikörper
PCR1 Antikörper
PNAS146 Antikörper
sr:nyz175 Antikörper
xmcm7 Antikörper

Bezeichner auf Proteinebene für MCM7

, , , , , , , , , , , , , , , , , , , , , , , , , , , CDC47 homolog DNA replication licensing factor MCM7 homolog of S. cerevisiae Cdc47 minichromosome maintenance deficient 7 hypothetical protein minichromosome maintenance protein 7 MCM7 minichromosome maintenance deficient 7 minichromosome maintenance complex component 7 DNA replication licensing factor MCM7-like minichromosome maintenance complex component 2 mini chromosome maintenance deficient 7 CDC47 homolog B CDC47-2p DNA replication licensing factor mcm7-B minichromosome maintenance protein 7-B xMCM7-B CG4978-PA Mcm7-PA minichromosome maintenance 7 minichromosome maintenance-PCR1 CDC47 homolog A CDC47p DNA replication licensing factor mcm7-A XMCM7 minichromosome maintenance protein 7-A p90 xMCM7-A Minichromosome maintenance protein 7

GENE ID	SPEZIES
4176	Homo sapiens
852501	Saccharomyces cerevisiae S288c
3645780	Candida albicans SC5314
288532	Rattus norvegicus
472460	Pan troglodytes
479737	Canis lupus familiaris
539924	Bos taurus
710766	Macaca mulatta
100401193	Callithrix jacchus
100442048	Pongo abelii
100481582	Ailuropoda melanoleuca
17220	Mus musculus
192333	Danio rerio
380414	Xenopus laevis
39014	Drosophila melanogaster
397852	Xenopus laevis
100719227	Cavia porcellus
2540630	Schizosaccharomyces pombe 972h-

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