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Human MCM3 Protein expressed in Wheat germ - ABIN1310549
Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia. in Journal of immunological methods 2011
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
, minichromosome maintenance 3
, minichromosome maintenance-PCR2
, MCM3 minichromosome maintenance deficient 3
, zygotic minichromosome maintenance protein 3
, DNA replication licensing factor MCM3
, DNA polymerase alpha holoenzyme-associated protein P1
, DNA replication factor MCM3
, RLF subunit beta
, cervical cancer proto-oncogene 5
, hRlf beta subunit
, minichromosome maintenance deficient 3
, replication licensing factor, beta subunit
, P1 homolog
, XRLF subunit beta
, maternal DNA replication licensing factor mcm3
, maternal minichromosome maintenance protein 3
, mini chromosome maintenance deficient