Decorin Proteine
(Decorin (DCN))
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. [provided by RefSeq, Jul 2008].
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DCN
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
DCN
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
SDS, WB, ELISA, MS
DCN
Spezies: Rind (Kuh)
Wirt: Hefe
Recombinant
> 90 %
ELISA
DCN
Spezies: Schimpanse
Wirt: Hefe
Recombinant
> 90 %
ELISA
DCN
Spezies: Schwein
Wirt: Hefe
Recombinant
> 90 %
ELISA
DCN
Spezies: Kaninchen
Wirt: Hefe
Recombinant
> 90 %
ELISA
Aktuelle Publikationen für unsere Decorin Proteine
: "The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21." in: Oncogene, Vol. 33, Issue 23, pp. 3054-63, (2014) (PubMed).: "Decorin is a novel VEGFR-2-binding antagonist for the human extravillous trophoblast." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 8, pp. 1431-43, (2011) (PubMed).
: "Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm." in: Cell death & disease, Vol. 2, pp. e209, (2011) (PubMed).
: "Granzyme B contributes to extracellular matrix remodeling and skin aging in apolipoprotein E knockout mice." in: Experimental gerontology, Vol. 46, Issue 6, pp. 489-99, (2011) (PubMed).
Aliase für Decorin Proteine
decorin (DCN) Proteinedecorin (Dcn) Proteine
decorin L homeolog (dcn.L) Proteine
decorin (dcn) Proteine
CSCD Proteine
cscd Proteine
DC Proteine
DSPG2 Proteine
dspg2 Proteine
mDcn Proteine
PG40 Proteine
pg40 Proteine
PGII Proteine
pgii Proteine
PGS2 Proteine
pgs2 Proteine
SLRR1B Proteine
slrr1b Proteine
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