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DAB2 Proteine

(Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

5 Treffer

DAB2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Produktnummer ABIN7122677
 
DAB2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Produktnummer ABIN1351061
 
DAB2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, Imm, PC, SDS
Produktnummer ABIN7421698
 
DAB2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2712271
 
DAB2 Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7584073
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Positive Control (PC)
    • SDS-PAGE (SDS)
    • Standard (STD)
  • Reaktivität
    • Human
    • Rat
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • Bindungsspezifität
    • AA 1-770
    • AA 2-768
    • AA 3-129
    • AA 350-450
  • Konjugat
    • His tag
    • GST tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
  • Hersteller
    • antibodies-online
    • CUSABIO
    • OriGene

Aliase für DAB2 Proteine

DAB2, clathrin adaptor protein (DAB2) Proteine
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (dab2) Proteine
Dab, mitogen-responsive phosphoprotein, homolog 2 (dab2) Proteine
DAB2, clathrin adaptor protein (Dab2) Proteine
disabled 2, mitogen-responsive phosphoprotein (Dab2) Proteine
5730435J12Rik Proteine
AA960054 Proteine
AI957090 Proteine
D15Wsu122e Proteine
D630005B22Rik Proteine
DOC-2 Proteine
Doc-2 Proteine
DOC2 Proteine
Doc2 Proteine
p96 Proteine
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