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Cyclin A1 Produkte

(Cyclin A1 (CCNA1))
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte Cyclin A1 Kategorien

Cyclin A1 Antikörper

High quality antibodies with extensive validation data.

Cyclin A1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Cyclin A1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Cyclin A1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7180926
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6261140
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse, Rat, Sheep
Applikation WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (4)
  • (2)
Kat. Nr. ABIN714026
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Cyclin A1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955144
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN4993357
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN4993356
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Cyclin A1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122517
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348428
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3122955
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Cyclin A1 Produkten

Abdel-Hamid, Zakaria, Nawaya, Eldomany, El-Shishtawy: "Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma." in: Recent patents on anti-cancer drug discovery, Vol. 18, Issue 2, pp. 187-199, (2023) (PubMed).

Zhao, Feng, Zhang, Kou, Li, Liu, Zhang, Cui, Chu, Shen, Min: "Inhibition of peripubertal sheep mammary gland development by cysteamine through reducing progesterone and growth factor production." in: Theriogenology, Vol. 89, pp. 280-288, (2017) (PubMed).

Yuan, Xi, Chen, Zhu, Kang, Zou, Wang, Bu: "STAT3 stimulates adipogenic stem cell proliferation and cooperates with HMGA2 during the early stage of differentiation to promote adipogenesis." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1360-1366, (2017) (PubMed).

Zeng, Ma, Chen, Qiu, Wu, Ling, Zeng: "Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." in: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).

Ghate, Das, Chaudhuri, Panja, Mandal: "Sundew plant, a potential source of anti-inflammatory agents, selectively induces G2/M arrest and apoptosis in MCF-7 cells through upregulation of p53 and Bax/Bcl-2 ratio." in: Cell death discovery, Vol. 2, pp. 15062, (2016) (PubMed).

Yuan, Zheng, Li, Xiang, Gao, Ran, Sun, Huang, Xie, Du, Xiao: "Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2." in: Acta biochimica et biophysica Sinica, Vol. 48, Issue 3, pp. 220-8, (2016) (PubMed).

Wang, Wang: "Studying the relationship between cell cycle and Alzheimer's disease by gold nanoparticle probes." in: Analytical biochemistry, Vol. 489, pp. 32-7, (2015) (PubMed).

Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: "An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7." in: PLoS ONE, Vol. 8, Issue 12, pp. e82293, (2013) (PubMed).

Ochsenreither, Majeti, Schmitt, Stirewalt, Keilholz, Loeb, Wood, Choi, Bleakley, Warren, Hudecek, Akatsuka, Weissman, Greenberg: "Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen." in: Blood, Vol. 119, Issue 23, pp. 5492-501, (2012) (PubMed).

Yang, Morosetti, Koeffler: "Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines." in: Cancer research, Vol. 57, Issue 5, pp. 913-20, (1997) (PubMed).

Synonyme und alternative Namen zu Cyclin A1

cyclin A1 (CCNA1), cyclin A1 (ccna1), cyclin A1 L homeolog (ccna1.L), CYCLIN A1;2 (CYCA1;2), cyclin A1 (Ccna1), cyclin A1 S homeolog (ccna1.S), CCNA1, ccna1, cyclin-A1, Cyclin-A1, cyclin-A1-2, fd14f08, MGC81965, MGC132235, wu:fd14f08, wu:fi20d12, zgc:111869

Bezeichner auf Proteinebene für Cyclin A1

  • cyclin-A1
  • cyclin A1
  • cyclin-A1-like
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