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CYB5R3 Produkte

(Cytochrome B5 Reductase 3 (CYB5R3))

Kategorien

This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010].

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Ausgewählte CYB5R3 Kategorien

CYB5R3 Antikörper

High quality antibodies with extensive validation data.

CYB5R3 ELISA Kits

Reliable ELISA kits for a wide range of species.

CYB5R3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CYB5R3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (5)
Kat. Nr. ABIN560603
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7160982
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN514976
Menge 50 μg
Datenblatt Datenblatt

Empfohlene CYB5R3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966213
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966212
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN813300
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CYB5R3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1350883
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122569
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350885
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CYB5R3 Produkten

Reed, Jarvis, Phillips, Arlt: "Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase." in: Mutation research, Vol. 852, pp. 503162, (2020) (PubMed).

Reed, Indra, Mrizova, Moserova, Schmeiser, Wolf, Henderson, Stiborova, Phillips, Arlt: "Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine." in: Toxicology and applied pharmacology, Vol. 366, pp. 64-74, (2019) (PubMed).

Reed, Mrizova, Barta, Indra, Moserova, Kopka, Schmeiser, Wolf, Henderson, Stiborova, Phillips, Arlt: "Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice." in: Archives of toxicology, Vol. 92, Issue 4, pp. 1625-1638, (2019) (PubMed).

Jakobs, Mikula, Havemeyer, Strzalkowska, Borowa-Chmielak, Dzwonek, Gajewska, Hennig, Ostrowski, Clement: "The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice." in: PloS one, Vol. 9, Issue 8, pp. e105371, (2014) (PubMed).

Havemeyer, Bittner, Wollers, Mendel, Kunze, Clement: "Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 34796-802, (2006) (PubMed).

Fernandez-Borja, Janssen, Verwoerd, Hordijk, Neefjes: "RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1." in: Journal of cell science, Vol. 118, Issue Pt 12, pp. 2661-70, (2005) (PubMed).

Synonyme und alternative Namen zu CYB5R3

cytochrome b5 reductase 3 (CYB5R3), cytochrome b5 reductase 3 (Cyb5r3), cytochrome b5 reductase 3 (cyb5r3), cytochrome b5 reductase 3 L homeolog (cyb5r3.L), NADH-cytochrome b5 reductase (CNM00240), NADH-cytochrome b5 reductase (Tb11.47.0018), NADH-cytochrome b5 reductase (cyb5r1), 0610016L08Rik, 2500002N19Rik, B5R, C85115, CB5R, DDBDRAFT_0218707, DDBDRAFT_0266821, DDB_0218707, DDB_0266821, Dia-1, DIA1, Dia1, dia1, fc32h03, Nadhcb5, RNNADHCB5, WU:AL591952.1-001, WU:AL591952.1-002, WU:AL591952.1-003, WU:Cyb5r3, wu:fc32h03, zgc:77071

Bezeichner auf Proteinebene für CYB5R3

  • NADH-cytochrome b5 reductase 3
  • NADH-cytochrome b5 reductase 3 membrane-bound form
  • NADH-cytochrome b5 reductase 3 soluble form
  • diaphorase-1
  • B5R
  • Diaphorase (NADH) (cytochrome b-5 reductase)
  • diaphorase 1
  • diaphorase 1 (NADH)
  • NADH-cytochrome b5 reductase
  • cytochrome b5 reductase 3
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