CTLA4 Proteine
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].
Ergebnisse filtern:
Möchten Sie unsere AI Suche ausprobieren?
87 Treffer
CTLA4
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS-PAGE
SDS, AcA
Active
CTLA4
Spezies: Human
Wirt: Baculovirus infected Insect Cells
Recombinant
> 95% by SDS-PAGE
SDS, AcA
Active
CTLA4
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
CTLA4
Spezies: Maus
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS - PAGE
SDS, AcA
Active
CTLA4
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
CTLA4
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
CTLA4
Spezies: Human
Wirt: CHO Cells
Recombinant
> 95 % , as determined by Coomassie stained SDS-PAGE.
FACS, ICFC
Active
CTLA4
Spezies: Maus
Wirt: CHO Cells
Recombinant
> 95 % , as determined by Coomassie stained SDS-PAGE.
FACS, ICFC
Active
CTLA4
Spezies: Human
Wirt: CHO Cells
Recombinant
> 95 % , as determined by Coomassie stained SDS-PAGE
AbP, STD, Func, PI
Active
CTLA4
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
WB, ELISA
Active
CTLA4
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
WB, ELISA
Active
CTLA4
Spezies: Human
Wirt: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
CTLA4
Spezies: Maus
Wirt: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
CTLA4
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
CTLA4
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
CTLA4
Spezies: Human
Wirt: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
CTLA4
Spezies: Human
Wirt: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
CTLA4
Spezies: Maus
Wirt: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
CTLA4
Spezies: Cynomolgus, Rhesusaffen
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
WB
Aktuelle Publikationen für unsere CTLA4 Proteine
: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." in: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).: "Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR." in: mAbs, Vol. 12, Issue 1, pp. 1803646, (2020) (PubMed).
: "CTLA4-Ig Directly Inhibits Osteoclastogenesis by Interfering With Intracellular Calcium Oscillations in Bone Marrow Macrophages." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, (2019) (PubMed).
: "Revealing the atomistic details behind the binding of B7-1 to CD28 and CTLA-4: A comprehensive protein-protein modelling study." in: Biochimica et biophysica acta. General subjects, Vol. 1862, Issue 12, pp. 2764-2778, (2019) (PubMed).
: "Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy." in: Nature communications, Vol. 10, Issue 1, pp. 3850, (2019) (PubMed).
: "Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques." in: PLoS pathogens, Vol. 15, Issue 9, pp. e1008015, (2019) (PubMed).
: "Comprehensive in vitro characterization of PD-L1 small molecule inhibitors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 12392, (2019) (PubMed).
: "PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways." in: Immunity, Vol. 51, Issue 6, pp. 1059-1073.e9, (2019) (PubMed).
: "Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens." in: Cancer cell, Vol. 33, Issue 6, pp. 1033-1047.e5, (2019) (PubMed).
: "Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes." in: Frontiers in pharmacology, Vol. 10, pp. 847, (2019) (PubMed).
Aliase für CTLA4 Proteine
cytotoxic T-lymphocyte associated protein 4 (CTLA4) Proteinecytotoxic T-lymphocyte-associated protein 4 (Ctla4) Proteine
CD Proteine
CD152 Proteine
Cd152 Proteine
CELIAC3 Proteine
CTLA-4 Proteine
Ctla-4 Proteine
CTLA4 Proteine
GRD4 Proteine
GSE Proteine
IDDM12 Proteine
Ly-56 Proteine
sCTLA4 Proteine
Haben Sie etwas anderes gesucht?
- CTIF/KIAA0427 Proteine
- CTHRC1 Proteine
- CTH Proteine
- CTGF Proteine
- CTF18 Proteine
- CTDSPL Proteine
- CTDSP2 Proteine
- CTDSP1 Proteine
- CTDP1 Proteine
- CTDNEP1A Proteine
- CTD Nuclear Envelope Phosphatase 1 Regulatory Subunit 1 Proteine
- CTD (Carboxy-Terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase Like 2 Proteine
- CTCFL Proteine
- CTCF Proteine
- CTBS Proteine
- CTBP2 Proteine
- CTBP1 Proteine
- CTAG2 Proteine
- CTAG1B Proteine
- CT45A5 Proteine
- CTNNA1 Proteine
- CTNNA2 Proteine
- CTNNA3 Proteine
- CTNNAL1 Proteine
- CTNNB1 Proteine
- CTNNBIP1 Proteine
- CTNNBL1 Proteine
- CTNND1 Proteine
- CTNND2 Proteine
- CTNS Proteine
- CTP Synthase Proteine
- CTPS2 Proteine
- CTRP5 Proteine
- CTRP6 Proteine
- CTRP7 Proteine
- CTSA Proteine
- CTSC Proteine
- CTSO Proteine
- CTU2 Proteine
- CUBN Proteine
Sie sind hier:
