Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to themm and inhibiting their deadenylation. Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules, and cell movement during embryogenesis. Required for pronephros development (By similarity).
custom-made
CIRBP
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
CIRBP
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Aktuelle Publikationen für unsere Cold Inducible RNA Binding Protein Proteine
Qiang, Yang, Wu, Zhou, Jacob, Dong, Kuncewitch, Ji, Yang, Wang, Fujita, Nicastro, Coppa, Tracey, Wang: "Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis." in: Nature medicine, Vol. 19, Issue 11, pp. 1489-95, (2013) (PubMed).
Mangé, Lacombe, Bascoul-Mollevi, Jarlier, Lamy, Rouanet, Maudelonde, Solassol: "Serum autoantibody signature of ductal carcinoma in situ progression to invasive breast cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 7, pp. 1992-2000, (2012) (PubMed).
Aliase für Cold Inducible RNA Binding Protein Proteine
cold inducible RNA binding protein (CIRBP) Proteine cold-inducible RNA-binding protein (EDI_107320) Proteine cold inducible RNA binding protein (Cirbp) Proteine cold inducible RNA binding protein S homeolog (cirbp.S) Proteine cold inducible RNA binding protein L homeolog (cirbp.L) Proteine cold inducible RNA binding protein (cirbp) Proteine cold inducible RNA binding protein b (cirbpb) Proteine A18 hnRNP Proteine APBP-1 Proteine cirbp Proteine CIRBP Proteine cirbp-a Proteine cirbp-b Proteine cirbp2 Proteine CIRP Proteine Cirp Proteine cirp Proteine cirp-1 Proteine cirp1 Proteine cirp2 Proteine R74941 Proteine Xcirp Proteine XCIRP Proteine XCIRP-1 Proteine xcirp2 Proteine zgc:136559 Proteine