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Human TXN2 ELISA Kit für Sandwich ELISA - ABIN825458
Mansego, De Marco, Ivorra, Lopez-Izquierdo, Morcillo, Rojo-Martínez, González-Albert, Martinez, Soriguer, Martín-Escudero, Redon, Chaves: The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control study. in Journal of translational medicine 2015
Prx3 (zeige PRDX3 ELISA Kits) and Trx2 comprise an adaptive system to sense changes in atmospheric oxygen tension and influence cellular injury responses through both detoxification of mitochondrial oxidants and regulation of mitochondrial redox-dependent signaling
Trx2 overexpression failed to attenuate hypoxia-induced human pulmonary arterial smooth muscle cells proliferation in vitro or hypoxia-induced Pulmonary hypertension in vivo.
study demonstrated that miR (zeige MLXIP ELISA Kits)-27a and -b, which are widely expressed in host cells, suppress SNAP25 (zeige SNAP25 ELISA Kits) and TXN2 expression through posttranscriptional gene silencing.
No evidence that SNPs in TRX2 have effects, but the rs4485648 polymorphism of the TrxR2 (zeige TXNRD2 ELISA Kits) gene might exert an independent effect on the development of Diabetic retinopathy.
Thioredoxin 2 Is a Novel E2-Interacting Protein That Inhibits the Replication of Classical Swine Fever Virus by promoting the nuclear translocation of the p65 (zeige GORASP1 ELISA Kits) subunit of NF-kappaB (zeige NFKB1 ELISA Kits).
The Grx2 (zeige GRX2 ELISA Kits) system could help to keep Trx2/1 reduced during an oxidative stress, thereby contributing to the anti-apoptotic signaling.
CERKL interacts with TRX2 and plays a novel key role in the regulation of the TRX2 antioxidant pathway.
TGF-beta (zeige TGFB1 ELISA Kits)-mediated expression of the epithelial-mesenchymal transition marker fibronectin (zeige FN1 ELISA Kits) was inhibited not only by chemicals that interfere with reactive oxygen species signaling but also by exogenously expressed mitochondrial thioredoxin.
We showed that overexpression of TRXs reduced cell death; TRX2 was expressed in the mitochondria, while TRX1 (zeige MLL ELISA Kits) was expressed in the cytoplasm.
knockdown of TRX-1 (zeige MLL ELISA Kits) or TRX-2 sensitizes cells to CYP2E1 (zeige CYP2E1 ELISA Kits)-induced oxidant stress partially via ASK-1 (zeige MAP3K5 ELISA Kits) and JNK1 (zeige MAPK8 ELISA Kits) signaling pathways. Both TRX-1 (zeige MLL ELISA Kits) and TRX-2 are important for defense against CYP2E1 (zeige CYP2E1 ELISA Kits)-induced oxidative stress.
This is the first demonstration of biochemical and physiological consequences caused by loss of Trx-2 in Drosophila.
gene for thioredoxin (DmTrx-2) was cloned and expressed, and the protein characterized
Drosophila thioredoxin can function as an anti-aging agent and as a suppressor of Parkin-associated endothelin receptor-like receptor - and poly-glutamine-induced neurotoxicity
Trx-2 affects lifespan in Drosophila. Mutants have a decreased lifespan.
The ventral signal observed from early stages colocalized with motor neuron markers Isl1 (zeige ISL1 ELISA Kits)/2 and FoxP1 (zeige FOXP1 ELISA Kits) and the strong ventral signal colocalizing with Isl1 (zeige ISL1 ELISA Kits)/2 was observed in all rostrocaudal segments of the spinal cord.
TRX-2 overexpression does not mitigate adverse effects of a high-calorie diet on synaptic plasticity
An essential role was identified for thioredoxin-2 in preserving cardiac function by suppressing mitochondrial reactive oxygen species.
The SirT1 (zeige SIRT1 ELISA Kits) regulates the expression of several antioxidant genes in bovine aortic endothelial cells, including Mn superoxide dismutase (zeige SOD2 ELISA Kits), catalase (zeige CAT ELISA Kits), peroxiredoxins 3 and 5, thioredoxin 2, thioredoxin reductase 2 (zeige TXNRD2 ELISA Kits), and uncoupling protein 2 (zeige UCP2 ELISA Kits).
This study shows that both fructose and glucose-sweetened liquid consumption results in fatty liver and upregulated thioredoxin-2 expression.
Both thioredoxin 2 and glutaredoxin 2 (zeige GRX2 ELISA Kits) contribute to the reduction of the mitochondrial 2-Cys (zeige DNAJC5 ELISA Kits) peroxiredoxin Prx3 (zeige PRDX3 ELISA Kits).
Data show that Nrf2 (zeige NFE2L2 ELISA Kits) activity was increased in WT MEFs at the 0 or -46 mV conditions, but was inhibited in Trx2 Tg MEFs under the same conditions.
the rapid E2-mediated activation of the Txn (zeige TXN ELISA Kits) pathway is an important step in the response of the mammalian uterus to estrogen.
Trx2 is an endogenous regulator of the mitochondrial permeability transition.
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
, thioredoxin, mitochondrial
, thioredoxin 2
, Thioredoxin 2
, thioredoxin nuclear gene encoding mitochondrial protein