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anti-CNTNAP1 (CNTNAP1) Antikörper

Bezeichnung:: anti-Contactin Associated Protein 1 Antikörper (CNTNAP1)

Auf www.antikoerper-online.de finden Sie aktuell 73 Contactin Associated Protein 1 (CNTNAP1) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CNTNAP1 Kits (23) und CNTNAP1 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 106 CNTNAP1 Produkte verfügbar.

Synonyme:: AI841080, Caspr, CNTNAP, CNTNAP1, NCP1, Nrxn4, p190, shm

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	CNTNAP1	8506	P78357
	CNTNAP1	84008	P97846
	CNTNAP1	53321	O54991
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Verknüpfte Pathways mit anti-CNTNAP1 Antikörper

Cell-Cell Junction Organization

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Am meisten referenzierte anti-CNTNAP1 Antikörper

Mammalian Monoclonal CNTNAP1 Primary Antibody für ISt, IHC - ABIN1304570 : Xing, Röth, Stratton, Chuang, Danne, Ellis, Ng, Kilpatrick, Merson: Adult neural precursor cells from the subventricular zone contribute significantly to oligodendrocyte regeneration and remyelination. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 (PubMed)
Show all 65 Pubmed References

Weitere Antikörper gegen CNTNAP1 Interaktionspartner

Human Contactin Associated Protein 1 (CNTNAP1) Interaktionspartner

We identified 9 novel CNTNAP1 variants in 6 families: three missense variants, four nonsense variants, one frameshift variant and one splice site variant. Significant polyhydramnios occurred in 6/7 pregnancies
E. coli exploits Caspr1 as a host receptor for penetration of the blood-brain barrier, resulting in meningitis
In two brothers with severe congenital hypotonia and foot deformities, we identified compound heterozygous variants in CNTNAP1, reporting the first causative missense variant, p.(Cys323Arg). Motor nerve conductions were markedly decreased.
CNTNAP1 mutations were found to induce characteristic ultrastructural lesions of the paranodal region.
report a consanguineous Arab family from Qatar with three children having an early lethal form of arthrogryposis multiplex congenita and a novel frameshift mutation in CNTNAP1
Mutations in CNTNAP1 and ADCY6 are responsible for severe arthrogryposis multiplex congenita with axoglial defects
VDAC1 and CNTNAP1 associate with gamma-secretase in detergent-resistant membranes and affect amyloid precursor protein processing.
A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.

Mouse (Murine) Contactin Associated Protein 1 (CNTNAP1) Interaktionspartner

E. coli exploits Caspr1 as a host receptor for penetration of the blood-brain barrier, resulting in meningitis
In Caspr1 mutants, there was a reduction in conductive properties of peripheral myelinated fibers and neuromuscular junction disintegration.
Caspr as a novel key regulator that controls the temporal specification of cell fate in radial glial cells of the developing cerebral cortex through Notch signaling
Simultaneous deletion of Caspr and Caspr2 disrupts the internodal organization of Kv1.2.
Caspr co-localizes and interacts with APP. Amyloid-beta (Abeta) 40 and Abeta42 generation were also reduced in HEK-APP cells by Caspr overexpression.
Caspr labeling was observed through much of the retina, including horizontal, bipolar, amacrine, and ganglion cells.
Clustering of Caspr at initial contact sites between OL processes and the axon requires glial expression of NF155 but not of contactin. Expression of membrane proteins along the axolemma is determined by the type of the contacting glial cells.
These results suggest that Caspr serves as a "transmembrane scaffold" that stabilizes the Caspr/contactin adhesion complex at the paranodal junction by connecting it to cytoskeletal components within the axon.
F3/contactin and caspr/paranodin traffic to the cell surface via a non-conventional pathway
Nogo-A interacts in trans with axonal Caspr at CNS paranodes, an interaction that may have a role in modulating axon-glial junction architecture and possibly K(+)-channel localization during development.
the Caspr/Cont complex is essential for the formation of axoglial SJ
Caspr protein is required for recruitment and retention of KCNQ4 at calyceal synapses in vestibular hair cells.
The Caspr gene has been identified in the neurological mutant shambling (shm) mouse and shown to encode the contactin-associated protein, which is a major component of the paranodal junction in myelinated nerves.
These results show a critical role for NCP1 in the delineation of specific axonal domains and the axon-glia interactions required for normal saltatory conduction.
Both NCP1 and CGT mutants develop large swellings accompanied by cytoskeletal disorganization and degeneration in the axons of cerebellar Purkinje neurons.

CNTNAP1 Antigen-Profil

Beschreibung des Gens

The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Alternative names and synonyms associated with CNTNAP1

contactin associated protein 1 (CNTNAP1) Antikörper
contactin associated protein 1 (cntnap1) Antikörper
contactin associated protein 1 (Cntnap1) Antikörper
contactin associated protein-like 1 (Cntnap1) Antikörper

AI841080 Antikörper
Caspr Antikörper
CNTNAP Antikörper
CNTNAP1 Antikörper
NCP1 Antikörper
Nrxn4 Antikörper
p190 Antikörper
shm Antikörper

Bezeichner auf Proteinebene für CNTNAP1

contactin associated protein 1 , contactin-associated protein 1-like , caspr1 , contactin-associated protein 1 , neurexin 4 , neurexin IV , neurexin-4 , p190 , paranodin , MHDNIV , neurexin 4 (contactin associated protein)

GENE ID	SPEZIES
454696	Pan troglodytes
100037844	Xenopus (Silurana) tropicalis
100390860	Callithrix jacchus
100450795	Pongo abelii
100481010	Ailuropoda melanoleuca
100559472	Anolis carolinensis
100604186	Nomascus leucogenys
8506	Homo sapiens
84008	Rattus norvegicus
100351604	Oryctolagus cuniculus
100719034	Cavia porcellus
100521039	Sus scrofa
490960	Canis lupus familiaris
540997	Bos taurus
428309	Gallus gallus
101111565	Ovis aries
53321	Mus musculus

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Show all anti-Contactin Associated Protein 1 (CNTNAP1) Antikörper with Pubmed References

Human Contactin Associated Protein 1 (CNTNAP1) Interaktionspartner

Mouse (Murine) Contactin Associated Protein 1 (CNTNAP1) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with CNTNAP1

Bezeichner auf Proteinebene für CNTNAP1