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CD40 Proteine

(CD40)
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

59 Treffer

CD40 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274186
 
CD40 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274177
 
CD40 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274188
 
CD40 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274182
 
CD40 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274173
 
CD40 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Produktnummer ABIN6961088
 
CD40 Spezies: Human Wirt: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Produktnummer ABIN1348641
 
CD40 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Pubmed 1 reference
Produktnummer ABIN2870723
 
CD40 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Pubmed 1 reference
Produktnummer ABIN2180793
 
CD40 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN2870589
 
CD40 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN5674593
 
CD40 Spezies: Cynomolgus Wirt: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7320972
 
CD40 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7320760
 
CD40 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Produktnummer ABIN1348644
 
CD40 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Produktnummer ABIN1348642
 
CD40 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
Produktnummer ABIN5853618
 
CD40 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Produktnummer ABIN7321208
 
CD40 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Produktnummer ABIN7321209
 
CD40 Spezies: Maus Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7491037
 
CD40 Spezies: Rhesusaffen Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN2870791
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Affinity Purification (AP)
    • Positive Control (PC)
    • Antibody Array (AA)
    • Mass Spectrometry (MS)
    • Activity Assay (AcA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Cynomolgus
    • Rat
    • Rhesus Monkey
    • Dog
    • Callithrix jacchus
    • Cow
    • Horse
    • Pig
    • Rabbit
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Human Cells
    • Escherichia coli (E. coli)
    • Yeast
    • Mammalian Cells
    • Wheat germ
    • CHO Cells
    • HEK-293T Cells
    • Insect Cells
  • Bindungsspezifität
    • AA 21-193
    • AA 24-193
    • AA 21-194
    • partial
    • AA 20-193
    • AA 1-151
    • AA 1-277
    • AA 26-187
    • AA 26-193
    • AA 77-249
    • Transcript Variant 1
    • full length
  • Konjugat
    • His tag
    • Fc Tag
    • Unkonjugiert
    • Fc Tag,AVI tag,Biotin
    • Fc Tag,His tag
    • GST tag
    • His tag,AVI tag,Biotin
    • His-Avi Tag,Biotin
    • His-DYKDDDDK-Strep II Tag
    • hIgG-His-tag
    • mFc Tag
    • mFc-His Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Hersteller
    • antibodies-online
    • ACROBiosystems
    • CUSABIO
    • ProSci
    • Cohesion Biosciences
    • OriGene

Aktuelle Publikationen für unsere CD40 Proteine

Upadhyaya, Lahdenranta, Hurov, Battula, Dods, Haines, Kleyman, Kristensson, Kublin, Lani, Ma, Mudd, Repash, Van Rietschoten, Stephen, You, Harrison, Chen, McDonnell, Brandish, Keen: "Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist." in: Journal for immunotherapy of cancer, Vol. 9, Issue 1, (2021) (PubMed).

Aghevlian, Wu, Raie, Tumbale, Kare, Seo, Ferrara: "Pre-clinical evaluation of immunoPET imaging using agonist CD40 monoclonal antibody in pancreatic tumor-bearing mice." in: Nuclear medicine and biology, Vol. 98-99, pp. 8-17 (PubMed).

Aliase für CD40 Proteine

CD40 molecule (CD40) Proteine
CD40 antigen (Cd40) Proteine
CD40 molecule (Cd40) Proteine
AI326936 Proteine
Bp50 Proteine
CDW40 Proteine
GP39 Proteine
HIGM1 Proteine
IGM Proteine
IMD3 Proteine
p50 Proteine
T-BAM Proteine
TNFRSF5 Proteine
Tnfrsf5 Proteine
TNFSF5 Proteine
TRAP Proteine
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