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anti-Human TJP1 Antikörper:
anti-Mouse (Murine) TJP1 Antikörper:
anti-Rat (Rattus) TJP1 Antikörper:
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Human Polyclonal TJP1 Primary Antibody für IF (cc), IF (p) - ABIN675024
Gu, Xue, Wei, Zhang, Li: Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats. in Neuroscience letters 2011
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Human Monoclonal TJP1 Primary Antibody für IF, WB - ABIN968282
Ebnet, Schulz, Meyer Zu Brickwedde, Pendl, Vestweber: Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1. in The Journal of biological chemistry 2000
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Human Monoclonal TJP1 Primary Antibody für IF, WB - ABIN968283
Hirase, Kawashima, Wong, Ueyama, Rikitake, Tsukita, Yokoyama, Staddon: Regulation of tight junction permeability and occludin phosphorylation by Rhoa-p160ROCK-dependent and -independent mechanisms. in The Journal of biological chemistry 2001
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Human Polyclonal TJP1 Primary Antibody für ICC, IF - ABIN4359733
Gangl, Reininger, Bernhard, Campana, Pree, Reisinger, Kneidinger, Kundi, Dolznig, Thurnher, Valent, Chen, Vrtala, Spitzauer, Valenta, Niederberger: Cigarette smoke facilitates allergen penetration across respiratory epithelium. in Allergy 2009
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Human Polyclonal TJP1 Primary Antibody für ICC, IF - ABIN4359735
McIntyre, Alev, Mechael, Salci, Lee, Fiebig-Comyn, Guezguez, Wu, Sheng, Bhatia: Expansive generation of functional airway epithelium from human embryonic stem cells. in Stem cells translational medicine 2014
Human Polyclonal TJP1 Primary Antibody für ELISA, WB - ABIN4359730
Zhong, Deane, Ali, Parisi, Shapovalov, OBanion, Stojanovic, Sagare, Boillee, Cleveland, Zlokovic: ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. in Nature neuroscience 2008
Human Polyclonal TJP1 Primary Antibody für IF - ABIN2192206
Balda, Anderson: Two classes of tight junctions are revealed by ZO-1 isoforms. in The American journal of physiology 1993
These results indicate the varying effects of 7-oxygenated cholesterol molecules on the expression and localization of ZO-1 depending on cell types, and suggest the contribution of 7-oxygeneted cholesterol molecules to the structural alteration of tight junctions.
CTR (zeige CALCR Antikörper) activates AKAP2 (zeige AKAP2 Antikörper)-anchored cAMP-dependent protein kinase A, which then phosphorylates tight junction proteins ZO-1 and claudin 3 (zeige CLDN3 Antikörper).
the Ras signaling pathway is involved in HIV-1 Tat (zeige TAT Antikörper)-induced changes in ZO-1 and NEP (zeige MME Antikörper).
decreased interaction between ZO-1 and occludin (zeige OCLN Antikörper) might contribute to the epiphora occurred in the transplanted submandibular glands
integration of claudin-2 (zeige CLDN2 Antikörper), occludin (zeige OCLN Antikörper) and ZO-1 is necessary for maintaining the function of the proximal tubular epithelium.
Endothelial cellsTLR4 strongly regulates retinal vessel permeability by reducing expression of occludin (zeige OCLN Antikörper) and zonula occludens 1.
The role of estrogens in the regulation of ZO-1 and estrogen receptors 1 and 2 was evaluated in human primary gut (zeige GUSB Antikörper) tissues by immunohistochemistry, immunofluorescence and qPCR.
Aberrant expression of the tight junction molecules claudin-1 (zeige CLDN7 Antikörper) and zonula occludens-1 mediates cell growth and invasion in oral squamous cell carcinoma cells.
ZO-1-occludin (zeige OCLN Antikörper) interactions regulate multiple phases of epithelial polarization by providing cell-intrinsic signals that are required for single lumen formation.
It is postulated that ZO-1, when not phosphorylated by PKC (zeige PRRT2 Antikörper), keeps Octn2 (zeige SLC22A5 Antikörper) in an active state, while elimination of this binding in DeltaPDZ mutant or after ZO-1 phosphorylation leads to diminution of Octn2 (zeige SLC22A5 Antikörper) activity.
STAT3 (zeige STAT3 Antikörper) activation downregulates the ZO-1 and occludin (zeige OCLN Antikörper) levels and increases the endothelial permeability through the induction of VEGF (zeige VEGFA Antikörper) production in retinal endothelial cells.
Cx43 (zeige GJA1 Antikörper) tethers the F-actin cytoskeleton through a ZO-1 linker and supports cell spreading and exploration during locomotion in cerebral endothelial cells.
Expression of Podocalyxin (zeige PODXL Antikörper), which positively regulates the formation of microvilli and the apical membrane, is repressed in embryoid bodies lacking both ZO-1 and ZO-2 (zeige TJP2 Antikörper) and this correlates with an aberrant submembranous localization of Ezrin (zeige EZR Antikörper).
Zonula occludens-1, occludin (zeige OCLN Antikörper) and E-cadherin (zeige CDH1 Antikörper) expression and organization in salivary glands
Tjp1 expression was decreased in glomerular diseases in human and animal models, our results indicate that the suppression of Tjp1 could directly aggravate glomerular disorders, highlights Tjp1 as a potential therapeutic target.
Arecoline increases the production of TNF-alpha (zeige TNF Antikörper) and induces protein redistribution of ZO-1.
Vcl (zeige VCL Antikörper) plays a crucial role in stabilizing gap junctions and myocyte integrity through direct interactions with ZO-1 and stabilization of CX43 (zeige GJA1 Antikörper).
Activation of RhoA (zeige RHOA Antikörper)/ROCK1 (zeige ROCK1 Antikörper) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin (zeige OCLN Antikörper)/ZO-1, which can be corrected by simvastatin.
Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C epsilon (zeige PRKCE Antikörper)-mediated zona occludens-1 phosphorylation at threonine 770/772.
cyclic strain modulates both the expression and phosphorylation state of occludin (zeige OCLN Antikörper) and ZO-1 in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
ZO-1 and occludin (zeige OCLN Antikörper) are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin (zeige OCLN Antikörper) at the blastocyst stage.
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
tight junction protein ZO-1
, zona occludens 1
, zona occludens protein 1
, zonula occludens 1 protein
, zonula occludens protein 1
, tight junction protein 1 (zona occludens 1)
, zonula occludens 1