BCMA Proteine
(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008].
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TNFRSF17
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
> 99 % as determined by SDS-PAGE
1 image
TNFRSF17
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
1 image
TNFRSF17
Spezies: Human
Wirt: Human Cells
Recombinant
>90 % as determined by reducing SDS-PAGE.
1 image
TNFRSF17
Spezies: Cynomolgus, Rhesusaffen
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
TNFRSF17
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>92 % as determined by SDS-PAGE.
Func
Active
TNFRSF17
Spezies: Human
Wirt: Yeast (Pichia pastoris)
Recombinant
> 90 % as determined by reducing SDS-PAGE.
TNFRSF17
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
TNFRSF17
Spezies: Human
Wirt: Mammalian Cells
Recombinant
Greater than 95 % as determined by SDS-PAGE.
WB, ELISA
TNFRSF17
Spezies: Maus
Wirt: Mammalian Cells
Recombinant
Greater than 95 % as determined by SDS-PAGE.
WB, ELISA
TNFRSF17
Spezies: Human
Wirt: Mammalian Cells
Recombinant
Greater than 95 % as determined by SDS-PAGE.
WB, ELISA
TNFRSF17
Spezies: Human, Maus
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
SDS
Active
TNFRSF17
Spezies: Cynomolgus, Rhesusaffen
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TNFRSF17
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 92 % by SDS-PAGE.
Active
TNFRSF17
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 80 %
SDS, WB, Imm, PC
TNFRSF17
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
TNFRSF17
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TNFRSF17
Spezies: Human
Wirt: Escherichia coli (E. coli)
> 98 % by SDS-PAGE and HPLC analyses.
Aktuelle Publikationen für unsere BCMA Proteine
: "Hypoxia Selectively Impairs CAR-T Cells In Vitro." in: Cancers, Vol. 11, Issue 5, (2019) (PubMed).: "CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth." in: Cancers, Vol. 10, Issue 9, (2018) (PubMed).
: "Selective APRIL blockade delays systemic lupus erythematosus in mouse." in: PLoS ONE, Vol. 7, Issue 2, pp. e31837, (2012) (PubMed).
: "BAFF production by antigen-presenting cells provides T cell co-stimulation." in: International immunology, Vol. 16, Issue 3, pp. 467-75, (2004) (PubMed).
: "T cell costimulation by the TNF ligand BAFF." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 11, pp. 6225-31, (2001) (PubMed).
: "A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth." in: The Journal of experimental medicine, Vol. 192, Issue 11, pp. 1677-84, (2000) (PubMed).
Aliase für BCMA Proteine
TNF receptor superfamily member 17 (Tnfrsf17) ProteineTNF receptor superfamily member 17 (TNFRSF17) Proteine
tumor necrosis factor receptor superfamily, member 17 (Tnfrsf17) Proteine
BCM Proteine
BCMA Proteine
CD269 Proteine
Tnfrsf13 Proteine
TNFRSF13A Proteine
Tnfrsf13a Proteine
TNFRSF17 Proteine
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