ASAP2 Produkte
(ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2))
Kategorien
This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
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Ausgewählte ASAP2 Kategorien
ASAP2 Antikörper
High quality antibodies with extensive validation data.
ASAP2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ASAP2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN563842
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN7265659
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Monkey, Mouse, Opossum, Rat
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN960087
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ASAP2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345787
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345789
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3089284
Menge
1 mg
Datenblatt
Datenblatt
Synonyme und alternative Namen zu ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (ASAP2), ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 L homeolog (asap2.L), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b (asap1b), ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (asap2), ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (Asap2), 6530401G17Rik, AMAP2, asap2, CENTB3, DDEF2, ddef2, Ddef2, Gm592, Gm1523, PAG3, PAP, Pap-alpha, SHAG1, si:dkey-37o8.2Bezeichner auf Proteinebene für ASAP2
- development and differentiation enhancing factor 2
- development- and differentiation-enhancing factor 2
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
- asap1
- PYK2 C terminus-associated protein
- arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2
- centaurin, beta 3
- development and differentiation-enhancing factor 2
- paxillin-associated protein with ARF GAP activity 3
- pyk2 C-terminus-associated protein
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