APPL1 Produkte
(Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
Kategorien
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008].
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Ausgewählte APPL1 Kategorien
APPL1 Antikörper
High quality antibodies with extensive validation data.
APPL1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene APPL1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7234818
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN565220
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7149501
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene APPL1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6205982
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene APPL1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121695
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345406
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345408
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren APPL1 Produkten
: "APPL1 promotes glucose uptake in response to mechanical stretch via the PKCζ-non-muscle myosin IIa pathway in C2C12 myotubes." in: Cellular signalling, Vol. 28, Issue 11, pp. 1694-702, (2016) (PubMed).: "Fiber type-specific differences in glucose uptake by single fibers from skeletal muscles of 9- and 25-month-old rats." in: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 67, Issue 12, pp. 1286-94, (2012) (PubMed).
: "A novel method to measure glucose uptake and myosin heavy chain isoform expression of single fibers from rat skeletal muscle." in: Diabetes, Vol. 61, Issue 5, pp. 995-1003, (2012) (PubMed).
: "Effects of polysaccharides from Morchella conica on nitric oxide production in lipopolysaccharide-treated macrophages." in: Applied microbiology and biotechnology, Vol. 94, Issue 3, pp. 763-71, (2012) (PubMed).
: "Mechanisms for increased insulin-stimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats." in: American journal of physiology. Endocrinology and metabolism, Vol. 300, Issue 6, pp. E966-78, (2011) (PubMed).
: "Insulin resistance for glucose uptake and Akt2 phosphorylation in the soleus, but not epitrochlearis, muscles of old vs. adult rats." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 108, Issue 6, pp. 1631-40, (2010) (PubMed).
: "APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function." in: Nature cell biology, Vol. 8, Issue 5, pp. 516-23, (2006) (PubMed).
: "Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2." in: Oncogene, Vol. 18, Issue 35, pp. 4891-8, (1999) (PubMed).
Synonyme und alternative Namen zu APPL1
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (Appl1), adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (Appl1), 2900057D21Rik, 7330406P05Rik, AI585782, APPL, AW209077, BB022931, C88264, DIP13, DIP13alpha, RGD1309388Bezeichner auf Proteinebene für APPL1
- AKT2 interactor
- DCC-interacting protein 13-alpha
- adapter protein containing PH domain, PTB domain and leucine zipper motif 1
- adaptor protein containing pH domain, PTB domain and leucine zipper motif 1
- dip13-alpha
- signaling adaptor protein DIP13alpha
- DIP13 alpha
- adaptor protein APPL like
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