APC Produkte
(Adenomatous Polyposis Coli (APC))
Kategorien
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008].
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Ausgewählte APC Kategorien
APC Antikörper
High quality antibodies with extensive validation data.
APC ELISA Kits
Reliable ELISA kits for a wide range of species.
APC Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene APC Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7439342
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7260669
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN1678690
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene APC ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6953476
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964614
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953477
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene APC Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121704
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345292
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505206
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren APC Produkten
: "Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum." in: Nature communications, Vol. 9, Issue 1, pp. 2830, (2018) (PubMed).: "Comparison of Selected Protein Levels in Tumour and Surgical Margin in a Group of Patients with Oral Cavity Cancer." in: Biochemical genetics, Vol. 55, Issue 4, pp. 322-334, (2017) (PubMed).
: "Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer." in: Experimental biology and medicine (Maywood, N.J.), Vol. 241, Issue 14, pp. 1531-9, (2017) (PubMed).
: "Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis." in: Oncogene, (2016) (PubMed).
: "Genetic reconstitution of tumorigenesis in primary intestinal cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 27, pp. 11127-32, (2013) (PubMed).
: "Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway." in: Journal of cell science, Vol. 121, Issue Pt 11, pp. 1793-802, (2008) (PubMed).
: "Cadherins, catenins and APC in pleural malignant mesothelioma." in: The Journal of pathology, Vol. 201, Issue 3, pp. 355-62, (2003) (PubMed).
Synonyme und alternative Namen zu APC
APC, WNT signaling pathway regulator (APC), adenomatous polyposis coli (apc), adenomatous polyposis coli protein, putative (Smp_139190), adenomatosis polyposis coli (Apc), APC, WNT signaling pathway regulator (Apc), adenomatous polyposis coli L homeolog (apc.L), AI047805, APC1, AU020952, AW124434, BTPS2, CC1, dp2, DP2, dp2.5, DP2.5, dp3, DP3, fap, fpc, GS, mAPC, Min, PPP1R46, RATAPC, xapcBezeichner auf Proteinebene für APC
- adenomatosis polyposis coli
- adenomatous polyposis coli protein
- multiple intestinal neoplasia
- adenomatosis polyposis coli tumor suppressor
- deleted in polyposis 2.5
- protein phosphatase 1, regulatory subunit 46
- adenomatous polyposis coli homolog
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