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Ferritin Antikörper (FE) Primary Antibody

FE Reaktivität: Human IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (5 references)
Produktnummer ABIN99122
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle Ferritin (FE) Antikörper anzeigen
    Ferritin (FE)
    Reaktivität
    • 81
    • 14
    • 13
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 32
    • 4
    • 2
    • 2
    Kaninchen
    Klonalität
    • 61
    • 32
    Polyklonal
    Konjugat
    • 58
    • 11
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Ferritin Antikörper ist unkonjugiert
    Applikation
    • 60
    • 35
    • 20
    • 10
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Kreuzreaktivität (Details)
    Cross reactivity against Ferritin from other tissues and species may occur but have not been specifically determined.
    Reinheit
    Anti-FERRITIN is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum as well as purified and partially purified Ferritin [Human Spleen].
    Endotoxin-Niveau
    Low Endotoxin : No
    Immunogen
    Ferritin [Human Spleen]
    Immunogen Type: Native Protein
    Isotyp
    IgG
  • Applikationshinweise
    ELISA Dilution: 1:5.000 - 1:20.000
    Immunohistochemistry Dilution: 1:200 - 1:1.000
    Western Blot Dilution: 1:5.000 - 1:2.000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Handhabung
    Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store vial at -20 °C or below prior to opening. This vial contains a relatively low volume of reagent (25 µL). To minimize loss of volume dilute 1:10 by adding 225 µL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below.
    Haltbarkeit
    Expiration date is one (1) year from date of opening.
  • Mai, Hamaï, Hienzsch, Cañeque, Müller, Wicinski, Cabaud, Leroy, David, Acevedo, Ryo, Ginestier, Birnbaum, Charafe-Jauffret, Codogno, Mehrpour, Rodriguez: "Salinomycin kills cancer stem cells by sequestering iron in lysosomes." in: Nature chemistry, Vol. 9, Issue 10, pp. 1025-1033, (2019) (PubMed).

    Goodwin, Dowdle, DeJesus, Wang, Bergman, Kobylarz, Lindeman, Xavier, McAllister, Nyfeler, Hoffman, Murphy: "Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9." in: Cell reports, Vol. 20, Issue 10, pp. 2341-2356, (2018) (PubMed).

    Kimura, Jia, Kumar, Choi, Gu, Mudd, Dupont, Jiang, Peters, Farzam, Jain, Lidke, Adams, Johansen, Deretic: "Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy." in: The EMBO journal, Vol. 36, Issue 1, pp. 42-60, (2017) (PubMed).

    Mancias, Pontano Vaites, Nissim, Biancur, Kim, Wang, Liu, Goessling, Kimmelman, Harper: "Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis." in: eLife, Vol. 4, (2016) (PubMed).

    Mancias, Wang, Gygi, Harper, Kimmelman: "Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy." in: Nature, Vol. 509, Issue 7498, pp. 105-9, (2014) (PubMed).

  • Target
    Ferritin (FE)
    Andere Bezeichnung
    Ferritin (FE Produkte)
    Synonyme
    1HCH, BEST:LD36673, CG2216, Dmel\\CG2216, FER1, FER1HCH, Fer-L, Fer1, Fer1HC, FerHCH, HCH, T21, T9, fer1, fer1hch, l(3)00451, l(3)j10B4, SFerH-1, SOF-35, SOF-5L, NV13011, ACP1, F8A5.24, F8A5_24, Ferritin 1 heavy chain homologue, ferritin light chain, ferritin, chromosome 26 open reading frame, human C10orf131, hyaluronan and proteoglycan link protein 2, NAD(P)-linked oxidoreductase superfamily protein, Fer1HCH, H-1, YPDSF_1340, ftnA, Ft, C26H10orf131, HAPLN2, AT1G60730
    Hintergrund
    Synonyms: Ferritin H subunit, Ferritin heavy chain like, Ferritin heavy polypeptide 1, Ferritin L subunit, Ferritin light chain like, Ferritin light polypeptide, Ferritin, heavy polypeptide, FTH
    Gen-ID
    2495
    UniProt
    P02794
    Pathways
    Transition Metal Ion Homeostasis
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