Thrombopoietin Antikörper
Kurzübersicht für Thrombopoietin Antikörper (ABIN969571)
Target
Alle Thrombopoietin (THPO) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- THPO Antibody
-
Aufreinigung
- Purified antibody
-
Immunogen
- Purified recombinant fragment of human THPO expressed in E. Coli.
-
Isotyp
- IgG2a
-
-
-
-
Applikationshinweise
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation." in: Blood, Vol. 114, Issue 8, pp. 1655-7, (2009) (PubMed).
: "Thrombopoietin level in patients with chronic liver diseases." in: Annals of hepatology, Vol. 7, Issue 3, pp. 235-44, (2008) (PubMed).
-
: "Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation." in: Blood, Vol. 114, Issue 8, pp. 1655-7, (2009) (PubMed).
-
- Thrombopoietin (THPO)
-
Andere Bezeichnung
- THPO
-
Hintergrund
- Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene.
-
Molekulargewicht
- 37.8 kDa
-
UniProt
- P40225
-
Pathways
- JAK-STAT Signalweg, Hormone Activity
Target
-